Biliopancreatic diversion surgery for morbid obesity is known to cause multiple vitamin deficiencies that may worsen during pregnancy. In the June issue of the Journal of AAPOS, the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus, a group of Australian clinicians report a child who was born blind as a result of Vitamin A deficiency caused by his mother's obesity surgery.
Clinical investigators from Australia documented the case of a woman who had undergone biliopancreatic diversion surgery for obesity 7 years before the birth of her child. At 9 weeks gestation, the mother was diagnosed with severe deficiencies of Vitamins A, D and K, as well as iron-deficiency anemia, which had been undetected prior to this point. Despite treatment, her serum vitamin A level remained critically low throughout the pregnancy. Her infant son had significant malformations of both eyes, and his vision remains poor despite treatment. For the fetus, the first 8 weeks of gestation are the most critical time for organs to develop, including the formation of the visual system,
Lead investigator Glen Gole, MD, FRANZCO, Department of Ophthalmology, Royal Children's Hospital and Discipline of Paediatrics and Child Health, University of Queensland, Brisbane, states, "The mother's description of night blindness, recurrent low vitamin A levels during the pregnancy, and demonstrated vitamin A deficiency in the neonate support vitamin A deficiency as the cause. This case illustrates that vitamin A is very important for normal eye development in the fetus, particularly for pregnant women who have undergone gastric bypass surgery in order to improve their fertility."
Commenting on the article, J AAPOS Editor-in-Chief David G. Hunter, MD, PhD, stated, "Weight-reduction surgery is becoming more common, especially with the potential for health benefits that result from reducing obesity. Unfortunately some forms of this surgery cause vitamin deficiency, and in this case the problem led to a birth defect that caused blindness in one child. We are not aware of any other cases of this particular problem, but it is important for any woman who has had this form of gastric bypass surgery to be checked for vitamin deficiency--and have it corrected—before considering having a baby."
The article is "Ocular malformation in a newborn secondary to maternal hypovitaminosis A" by Hannah Gilchrist, MBBS, Deepa A. Taranath, MS, FRANZCO, and Glen A. Gole, MD, FRANZCO. It appears in the Journal of AAPOS, Volume 14, Issue 3, (June 2010) published by Elsevier. doi:10.1016/j.jaapos.2010.01.015
Lynelle Korte | EurekAlert!
Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung
High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences