The authors belong to a multidisciplinary, international team led by Dr. Maddalena Barba, researcher at the Regina Elena National Cancer Institute of Rome, Central Italy.
"In recent years, the scientific evidence linking vitamin D to breast cancer has grown notably. Several systematic reviews including randomized clinical trials have recently focused on vitamin D and health outcomes. However, so far, no systematic review has specifically addressed the role of vitamin D supplementation in breast cancer prevention” says Prof. Antonio Giordano, an internationally renowned oncologist engaged for years in the fight against breast cancer.
"The conduct of a systematic review allows to collate all evidence that fits pre-specified eligibility criteria on a specific research question. It is always desirable to review a body of data systematically in that such an assessment holds the potentials to orient future steps and health priorities in a specific research setting. This approach is particularly appropriate when dealing with issues with broad reflections in terms of public health, such as breast cancer related outcomes” adds Prof. Giordano
In this study, the researchers focused on breast cancer, the most commonly diagnosed cancer and the second leading cause of cancer death in women from Western countries. "This systematic review was carried out in full agreement with the methods applied by the Cochrane collaboration, an international not-for-profit organization preparing, maintaining and promoting the accessibility of systematic reviews of the effects of health care and prevention worldwide. Our work contributes a comprehensive appraisal of the evidence stemming from randomized controlled trials on vitamin D supplementation for breast cancer prevention. Based on our results and considering the intrinsic limitations of the scientific evidence examined, vitamin D supplementation seems not to be associated with a reduced risk of breast cancer development in women. However, the scientific panorama related to the association of interest is still limited and overall inadequate to draw firm conclusions” clarifies Dr Barba.
“New trials specifically tailored on the vitamin D-cancer- binomious are in progress and should provide additional information in a few years’ time. Methodological tools and key tenets of vitamin D metabolism and biological activities will help interpret the upcoming results” concludes Prof. Giordano.
Barbara Colombo | Newswise
Multi-year study finds 'hotspots' of ammonia over world's major agricultural areas
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The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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