The authors belong to a multidisciplinary, international team led by Dr. Maddalena Barba, researcher at the Regina Elena National Cancer Institute of Rome, Central Italy.
"In recent years, the scientific evidence linking vitamin D to breast cancer has grown notably. Several systematic reviews including randomized clinical trials have recently focused on vitamin D and health outcomes. However, so far, no systematic review has specifically addressed the role of vitamin D supplementation in breast cancer prevention” says Prof. Antonio Giordano, an internationally renowned oncologist engaged for years in the fight against breast cancer.
"The conduct of a systematic review allows to collate all evidence that fits pre-specified eligibility criteria on a specific research question. It is always desirable to review a body of data systematically in that such an assessment holds the potentials to orient future steps and health priorities in a specific research setting. This approach is particularly appropriate when dealing with issues with broad reflections in terms of public health, such as breast cancer related outcomes” adds Prof. Giordano
In this study, the researchers focused on breast cancer, the most commonly diagnosed cancer and the second leading cause of cancer death in women from Western countries. "This systematic review was carried out in full agreement with the methods applied by the Cochrane collaboration, an international not-for-profit organization preparing, maintaining and promoting the accessibility of systematic reviews of the effects of health care and prevention worldwide. Our work contributes a comprehensive appraisal of the evidence stemming from randomized controlled trials on vitamin D supplementation for breast cancer prevention. Based on our results and considering the intrinsic limitations of the scientific evidence examined, vitamin D supplementation seems not to be associated with a reduced risk of breast cancer development in women. However, the scientific panorama related to the association of interest is still limited and overall inadequate to draw firm conclusions” clarifies Dr Barba.
“New trials specifically tailored on the vitamin D-cancer- binomious are in progress and should provide additional information in a few years’ time. Methodological tools and key tenets of vitamin D metabolism and biological activities will help interpret the upcoming results” concludes Prof. Giordano.
Barbara Colombo | Newswise
Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung
Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
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For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
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An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
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