A new study shows that the Gardasil vaccine reduces the likelihood of human papillomavirus (HPV)-related disease recurring after teen and adult women already have had surgery to remove cancer or certain pre-cancerous changes, said Warner Huh, M.D., an associate professor in the UAB Division of Gynecologic Oncology and lead presenter on the study.
The findings were announced March 15 at the annual meeting of the Society of Gynecological Oncologists in Chicago.
The study shows that Gardasil reduces by approximately 40 percent the chances that more cancer or pre-cancerous changes will occur in the cervix, vagina and vulva up to 3.8 years after a female has surgery for one of those conditions.
Huh said the findings are important because they answer a question many women and their doctors have been asking - does an HPV vaccine help treat virus-related changes in the body after women have surgery to treat similar changes?
"Based on this study, the data is compelling and suggests it does help to treat virus-related changes," Huh said. "Knowing that Gardasil also may offer postoperative protection from recurrent disease will be crucial in follow-up care and overall health planning for teens and women."
The vaccine is approved to fight the four HPV strains believed to cause 70 percent of cervical cancers and more than 90 percent of genital warts
The study involved 17,622 women ages 15 to 26 from two clinical trials, some who were vaccinated and some who were not. Hundreds of study participants had surgery to remove cancer or certain pre-cancerous changes of the cervix, vagina and vulva and to remove genital warts.
Huh said the results are encouraging because patients treated for HPV-related disease are known to be at higher risk for contracting the same disease post-operatively. Reducing the risk and need of a secondary procedure is an important step in improving women's care, he said.
*Note: Huh maintains a consulting relationship with Gardasil-maker Merck & Co., Inc.About the UAB Division of Gynecologic Oncology
Troy Goodman | EurekAlert!
Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT
Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
06.12.2016 | Materials Sciences
06.12.2016 | Medical Engineering
06.12.2016 | Power and Electrical Engineering