Older veterans who have experienced a traumatic brain injury (TBI) are 60 percent more likely to later develop dementia than veterans without TBI, according to a study published in the June 25, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The study also found that veterans with a history of TBI developed dementia about two years earlier than those without TBI who had developed dementia.
“These findings suggest that a history of TBI contributes risk for dementia in later life in veterans. If we assume that this relationship is causal, it seems likely that the same increased risk probably occurs with TBI in the civilian population as well,” said study author Deborah E. Barnes, PhD, MPH, of the University of California, San Francisco and the San Francisco Veterans Affairs Medical Center and a member of the American Academy of Neurology.
The study involved 188,784 veterans with an average age of 68 at the start of the study. All were free of dementia at the start of the study and had at least one visit to a VA health care facility at the start of the study and again an average of seven years later.
A total of 1,229 of the veterans had a TBI diagnosis. During the follow-up period, 196 veterans with TBI, or 16 percent, developed dementia, compared to 18,255, or 10 percent of those without TBI. After adjusting for other factors that could affect the risk of dementia, such as diabetes, high blood pressure, depression and alcohol abuse, researchers determined that veterans with TBI were 60 percent more likely to develop dementia than those without TBI.
On average, veterans with TBI developed dementia two years earlier than those without TBI, or at age 78.5 compared to 80.7. Also, those who did not develop dementia died 2.3 years earlier if they had a TBI versus no TBI (77.0 years versus 79.3 years). The researchers also found that the risk of dementia was higher in veterans with TBI who also had depression, post-traumatic stress disorder or cerebrovascular disease than in those with either TBI or these other conditions alone.
“This study convincingly shows that mild trauma has a role in increasing the risk of dementia and sheds light on the more complex relationship between medical and psychiatric diseases with TBI in the development of the future risk of dementias. Neuroscientists must take a careful and comprehensive approach and avoid oversimplified claims of causality,” said Rodolfo Savica, MD, MSc, of the University of Utah School of Medicine in Salt Lake City, and a member of the American Academy of Neurology, who wrote an editorial accompanying the study.
The study was supported by the U.S. Department of Defense/NCIRE and the National Institutes of Health.
To learn more about traumatic brain injury and dementia, please visit www.aan.com/patients.
The American Academy of Neurology, an association of more than 28,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson’s disease and epilepsy.
Rachel L. Seroka
Manager, Media and Public Relations
American Academy of Neurology
201 Chicago Avenue
Minneapolis, MN 55415
Ph: 612-928-6129 Mobile: 612-807-6968 Fax: 612-454-2744
Rachel L. Seroka | American Academy of Neurology
High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg
Brain connectivity reveals hidden motives
04.03.2016 | Universität Zürich
In the Beyond EUV project, the Fraunhofer Institutes for Laser Technology ILT in Aachen and for Applied Optics and Precision Engineering IOF in Jena are developing key technologies for the manufacture of a new generation of microchips using EUV radiation at a wavelength of 6.7 nm. The resulting structures are barely thicker than single atoms, and they make it possible to produce extremely integrated circuits for such items as wearables or mind-controlled prosthetic limbs.
In 1965 Gordon Moore formulated the law that came to be named after him, which states that the complexity of integrated circuits doubles every one to two...
Characterization of high-quality material reveals important details relevant to next generation nanoelectronic devices
Quantum mechanics is the field of physics governing the behavior of things on atomic scales, where things work very differently from our everyday world.
When current comes in discrete packages: Viennese scientists unravel the quantum properties of the carbon material graphene
In 2010 the Nobel Prize in physics was awarded for the discovery of the exceptional material graphene, which consists of a single layer of carbon atoms...
The trend-forward world of display technology relies on innovative materials and novel approaches to steadily advance the visual experience, for example through higher pixel densities, better contrast, larger formats or user-friendler design. Fraunhofer ISC’s newly developed materials for optics and electronics now broaden the application potential of next generation displays. Learn about lower cost-effective wet-chemical printing procedures and the new materials at the Fraunhofer ISC booth # 1021 in North Hall D during the SID International Symposium on Information Display held from 22 to 27 May 2016 at San Francisco’s Moscone Center.
Staphylococcus aureus usually is a formidable bacterial pathogen. Sometimes, however, weakened forms are found in the blood of patients. Researchers of the University of Würzburg have now identified one mutation responsible for that phenomenon.
Staphylococcus aureus is a bacterium that is frequently found on the human skin and in the nose where it usually behaves inconspicuously. However, once inside...
24.05.2016 | Event News
20.05.2016 | Event News
19.05.2016 | Event News
24.05.2016 | Physics and Astronomy
24.05.2016 | Earth Sciences
24.05.2016 | Trade Fair News