Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Successful periodontal therapy may reduce the risk of preterm birth

15.09.2010
A collaboration led by a periodontal researcher from the University of Pennsylvania School of Dental Medicine has found a possible link between the success of gum-disease treatment and the likelihood of giving birth prematurely, according to a study published in the journal BJOG: An International Journal of Obstetrics and Gynaecology.

While a number of factors are associated with an increased rate of preterm birth, such as low body-mass index, alcohol consumption and smoking, the study adds to the body of research that suggests oral infection may also be associated with such an increase.

The study looked at 322 pregnant women, all with gum disease. Half the group was given oral-hygiene instruction and treated with scaling and root planning, which consists of cleaning above and below the gum line. The second half received only oral-hygiene instruction.

The incidence of preterm birth was high in both the treatment group and the untreated group: 52.4 percent of the women in the untreated control group had a preterm baby compared with 45.6 percent in the treatment group. These differences were not statistically significant.

However, researchers then looked at whether the success of periodontal treatment was associated with the rate of preterm birth. Participants were examined 20 weeks after the initial treatment, and success was characterized by reduced inflammation, no increase in probing depth and loosening of the teeth.

Within the treatment group of 160 women, 49 were classified as having successful gum treatment and only four, or 8 percent, had a preterm baby. In comparison, 111 women had unsuccessful treatment and 69, or 62 percent, had preterm babies.

The results show that pregnant women who were resistant to the effects of scaling and root planning were significantly more likely to deliver preterm babies than those for whom it was successful.

The mean age of the women in the study was 23.7 years; 87.5 percent were African-American, and 90 percent had not seen a dentist for tooth cleaning.

"First and foremost, this study shows that pregnant women can receive periodontal treatment safely in order to improve their oral health," said Marjorie Jeffcoat, professor of periodontics at Penn Dental Medicine and lead author of the paper. "Second, in a high risk group of pregnant women, such as those patients who participated in this study, successful periodontal treatment when rendered as an adjunct to conventional obstetric care may reduce the incidence of preterm birth."

Future papers will address the role of antimicrobial mouth rinses in reducing the incidence of preterm birth.

"Researchers have previously suggested that severe gum infections cause an increase in the production of prostaglandin and tumour necrosis factor, chemicals which are associated with preterm labor," Philip Steer, editor-in-chief of BJOG, said. "This new study shows a strong link between unsuccessful gum-disease treatment and preterm birth; however, we need to bear in mind that 69 percent of women failed to respond to the dental treatment given. Therefore, more effective treatment will need to be devised before we can be sure that successful treatment improves outcome, rather than simply being a marker of pregnancies with a lower background level of inflammation that will go to term anyway."

The study was conducted by Jeffcoat, Mary Sammel, Bonnie Clothier and Annette Catlin of Penn Dental Medicine; Samuel Parry of the Department of Maternal and Fetal Medicine at Penn's School of Medicine; and George Macones of Washington University in St. Louis.

The study was funded by the Commonwealth of Pennsylvania and an educational grant from the Procter and Gamble Company.

Jordan Reese | EurekAlert!
Further information:
http://www.upenn.edu

More articles from Studies and Analyses:

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

nachricht Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

Scientist invents way to trigger artificial photosynthesis to clean air

26.04.2017 | Materials Sciences

Ammonium nitrogen input increases the synthesis of anticarcinogenic compounds in broccoli

26.04.2017 | Agricultural and Forestry Science

SwRI-led team discovers lull in Mars' giant impact history

26.04.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>