However, the efficacy of this treatment in patients with severe 2009 H1N1 influenza is unknown. A study published in the February 15 issue of Clinical Infectious Diseases suggests that convalescent plasma may reduce the death rate in patients severely ill with this type of influenza. (Please see below for a link to the embargoed study online.)
From September 2009 through June 2010, patients from a hospital cluster in Hong Kong with severe 2009 H1N1 infection requiring intensive care were recruited for the study. Of the 93 patients in the study, 20 received the plasma treatment. Prior patients who had recovered from H1N1 infection provided the convalescent plasma for the study. The 73 members of the study who declined the treatment were the study controls.
Mortality in the treatment group was 20 percent, compared to 55 percent in the non-treatment group. The viral load in the treatment group also decreased at a higher rate than in the control group. None of the patients developed adverse events from the treatment.
"One of the benefits of convalescent plasma treatment in patients with severe influenza A infection is that it does not suffer from the problem of drug resistance," said study author Kowk-Yung Yuen, MD, of the University of Hong Kong in China. "Additionally, it would remain effective until the virus has changed significantly enough to affect immunity. This form of treatment may be useful in future novel viral infections."
NOTE: The study is available online. It is embargoed until 12:01 a.m. EST on Wednesday, Jan. 19, 2011:
"Convalescent Plasma Treatment Reduced Mortality in Patients With Severe Pandemic Influenza A (H1N1) 2009 Virus Infection" http://www.oxfordjournals.org/our_journals/cid/ciq106.pdf
Founded in 1979, Clinical Infectious Diseases publishes clinical articles twice monthly in a variety of areas of infectious disease, and is one of the most highly regarded journals in this specialty. It is published under the auspices of the Infectious Diseases Society of America (IDSA). Based in Arlington, Va., IDSA is a professional society representing more than 9,000 physicians and scientists who specialize in infectious diseases. For more information, visit www.idsociety.org
John Heys | EurekAlert!
New study from the University of Halle: How climate change alters plant growth
12.01.2018 | Martin-Luther-Universität Halle-Wittenberg
Disarray in the brain
18.12.2017 | Universität zu Lübeck
Physicists have developed a technique based on optical microscopy that can be used to create images of atoms on the nanoscale. In particular, the new method allows the imaging of quantum dots in a semiconductor chip. Together with colleagues from the University of Bochum, scientists from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute reported the findings in the journal Nature Photonics.
Microscopes allow us to see structures that are otherwise invisible to the human eye. However, conventional optical microscopes cannot be used to image...
On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.
We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
23.01.2018 | Life Sciences
23.01.2018 | Earth Sciences
23.01.2018 | Physics and Astronomy