Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study shows pregnant mother's diet impacts infant's sense of smell

01.12.2010
Odors in womb sensitize fetus to smells, alters brain development

A major new study shows that a pregnant mother's diet not only sensitizes the fetus to those smells and flavors, but physically changes the brain directly impacting what the infant eats and drinks in the future.

"This highlights the importance of eating a healthy diet and refraining from drinking alcohol during pregnancy and nursing," said Josephine Todrank, PhD, who conducted the two-year study while a visiting scientist at the University of Colorado School of Medicine. "If the mother drinks alcohol, her child may be more attracted to alcohol because the developing fetus "expects" that whatever comes from the mother must be safe. If she eats healthy food, the child will prefer healthy food."

Researchers studying mice found that the pups' sense of smell is changed by what their mothers eat, teaching them to like the flavors in her diet. At the same time, they found significant changes in the structure of the brain's olfactory glomeruli, which processes smells, because odors in the amniotic fluid affect how this system develops.

"This is the first study to address the changes in the brain that occur upon steady exposure to flavors in utero and early in postnatal life when the newborn is receiving milk from the mother," said Diego Restrepo, PhD, co-director of the Center for NeuroScience at the University of Colorado School of Medicine and sponsor of the study. "During these periods the pup is exposed to flavors found in the food the mom is eating."

The research, he said, could have important public health implications.

"Many diseases plaguing society involve excess consumption or avoidance of certain kinds of foods," said Restrepo, a professor of cell and developmental biology. "Understanding the factors that determine choice and ingestion, particularly the early factors, is important in designing strategies to enhance the health of the infant, child, and adult."

In her study, Todrank, now a research fellow with collaborator Giora Heth, PhD, at the Institute of Evolution at the University of Haifa, Israel, fed one group of pregnant and nursing mice a bland diet and another a flavored diet. At weaning age, the pups from mothers on the flavored diet had significantly larger glomeruli than those on the bland diet. They also preferred the same flavor their mother ate, while the other pups had no preference.

"Exposure to odor or flavor in the womb elicits the preference but also shapes the brain development," said Todrank, whose work was funded by a grant from the National Institutes of Health and was published Dec. 1, 2010 in the Proceedings of the Royal Society B, a major biological research journal.

"From the fetus' point of view, whatever is in the womb is considered "good". If your mother ate it and survived to give birth to you then it was probably safe," she said. "This is a good strategy for a mouse that is foraging for food. It treats those same foods as safe."

Due to the similarities in mammalian development, she said, there is no reason to think that experiments would produce different results in humans.

"What an expectant mother chooses to eat and drink has long-term effects – for better or worse – on her child's sensory anatomy as well his or her odor memory and food preferences in the future," Todrank said. "It is not yet clear how long these changes and preferences last, but we are currently investigating that question."

Faculty at the University of Colorado Denver's School of Medicine work to advance science and improve care. These faculty members include physicians, educators and scientists at University of Colorado Hospital, The Children's Hospital, Denver Health, National Jewish Health, and the Denver Veterans Affairs Medical Center. Degrees offered by the UC Denver School of Medicine include doctor of medicine, doctor of physical therapy, and masters of physician assistant studies. The School is located on the University of Colorado's Anschutz Medical Campus, one of four campuses in the University of Colorado system. For additional news and information, please visit the UC Denver newsroom online.

David Kelly | EurekAlert!
Further information:
http://www.ucdenver.edu

More articles from Studies and Analyses:

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

nachricht Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>