Rotaxanes, one family of such molecules, are tiny, mechanically interlocked structures that consist of a dumbell-shaped molecule whose rod section is encircled by a ring. These structures behave as molecular "machines," with the ring moving along the rod from one station to another when stimulated by a chemical reaction, light or acidity.
To realize the potential of these molecular machines, however, it is necessary to understand and to measure their function at the nanoscale. Previous methods for observing their operation have involved chemical measurements in solution and studying collections of them attached to surfaces, but neither has provided an accurate picture of their function in environments that are relevant to molecular-device operation.
Now, a multidisciplinary team of researchers from UCLA, Northwestern University, UC Merced, Pennsylvania State University and Japan has succeeded in observing single-molecule interactions of bistable rotaxanes functioning in their native environment.
The team's findings are published in the current edition of the journal ACS Nano.
Led by Paul Weiss from UCLA and Fraser Stoddart from Northwestern University, the team developed a molecular design that firmly attached rotaxanes to a surface, enabling them to be individually examined in their native environment by a scanning tunneling microscope (STM). Using this technology, the researchers were able to record station changes by the rotaxanes' rings along their rods in response to electrochemical signals.
Previously, rotaxanes had to be grouped for study because of their mobility and flexibility when attached to surfaces. And because STM instruments utilize an atomically thin tip to feel out nanoscale surfaces ¯ in much the same way a blind person reads Braille ¯ the rotaxanes' flexible nature made it difficult to study them individually. The research team's molecular design, however, helped significantly reduce this flexibility.
The STM developed by the team enables much more detailed studies of molecular machines, leading to greater understanding of how they interact with their neighbors and how they might work together in nanoelectromechanical devices.
Paul Weiss, distinguished professor of chemistry and biochemistry, holds UCLA's Fred Kavli Chair in Nanosystems Sciences and is director of the California NanoSystems Institute (CNSI) at UCLA. Fraser Stoddart is the Board of Trustees Professor of Chemistry and director of the Center for the Chemistry of Integrated Systems (CCIS) at Northwestern University.
The work was funded by the National Science Foundation, the Semiconductor Research Corporation and the Kavli Foundation.
The California NanoSystems Institute at UCLA is an integrated research center operating jointly at UCLA and UC Santa Barbara whose mission is to foster interdisciplinary collaborations for discoveries in nanosystems and nanotechnology; train the next generation of scientists, educators and technology leaders; and facilitate partnerships with industry, fueling economic development and the social well-being of California, the United States and the world. The CNSI was established in 2000 with $100 million from the state of California and an additional $250 million in federal research grants and industry funding. At the institute, scientists in the areas of biology, chemistry, biochemistry, physics, mathematics, computational science and engineering are measuring, modifying and manipulating the building blocks of our world — atoms and molecules. These scientists benefit from an integrated laboratory culture enabling them to conduct dynamic research at the nanoscale, leading to significant breakthroughs in the areas of health, energy, the environment and information technology.
For more news, visit the UCLA Newsroom and follow us on Twitter.
Mike Rodewald | EurekAlert!
The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung
A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg
A Swedish-German team of researchers has cleared up a key process for the artificial production of silk. With the help of the intense X-rays from DESY's...
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
24.01.2017 | Physics and Astronomy
24.01.2017 | Life Sciences
24.01.2017 | Health and Medicine