Led by Dr. Amit Garg, a researcher at Lawson Health Research Institute and nephrologist at London Health Sciences Centre, the results provide important safety reassurances to donors, their recipients and health care professionals. In the general population, there is a strong link between reduced kidney function and an increased risk of heart disease. Previous studies suggest no evidence of a higher risk for living kidney donors, however, a consensus among health care providers had not been reached.
Dr. Garg's study involved 2,028 Ontarians who donated a kidney between 1992 and 2009, and 2,0280 healthy non-donors for comparison. "We manually reviewed the medical charts of over 2000 living kidney donors in Ontario and linked this information to universal healthcare databases to reliably follow major cardiovascular events," says Dr. Garg.
Despite reduced kidney function in the donors, the researchers found that donors had a lower risk of death and heart disease compared to non-donors. Dr. Garg is the kidney specialist who evaluates all individuals in Southwestern Ontario who are interested in becoming a kidney donor. According to Dr. Garg, potential donors must pass a rigorous approval process to be considered for living kidney donation, and in such, only the healthiest people are considered.
There has been a trend towards relaxing the selection criteria in order to help with Canada's organ donation shortage. However, Dr. Garg says this study does not inform such changes in the selection process; the long-term outcomes of these new types of donors needs further study.
According to an accompanying editorial by researchers at the University of Michigan, the study resolves the uncertainty that persists about the full extent of risks assumed by living kidney donors and makes an important contribution to our understanding of long-term consequences of living kidney donation.
"We did this study because better knowledge of major cardiovascular events in people who become living kidney donors maintains public trust in the transplantation system, informs the choices of potential donors and recipients, and guides follow-up care to maintain good long-term health," says Dr. Garg.
The study will be published in an upcoming issue of the British Medical Journal and can be found online at BMJ.com today.
Julia Capaldi | EurekAlert!
The importance of biodiversity in forests could increase due to climate change
17.11.2017 | Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv) Halle-Jena-Leipzig
Win-win strategies for climate and food security
02.10.2017 | International Institute for Applied Systems Analysis (IIASA)
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.
Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...
15.11.2017 | Event News
15.11.2017 | Event News
30.10.2017 | Event News
21.11.2017 | Physics and Astronomy
21.11.2017 | Materials Sciences
21.11.2017 | Health and Medicine