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Study Finds Washington State Pediatricians Receiving Regular Requests for Alternative Childhood Immunization Schedules

First of its kind study examines alternative immunization schedule occurrence rates in Washington state and pediatricians’ comfort level using alternative schedules

Seventy-seven percent of Washington state pediatricians report that they are sometimes or frequently asked to provide alternative childhood vaccine schedules for their patients, according to a new study from Seattle Children’s Research Institute.

Researchers also found that 61 percent of Washington state pediatricians are comfortable using an alternative schedule when asked by a parent. The study, “Washington State Pediatricians’ Attitudes Toward Alternative Childhood Immunization Schedules,” is published in the December 2011 issue of Pediatrics and is the first to evaluate pediatricians’ attitudes towards alternative schedules.

“When discussing alternative childhood immunization schedules, pediatricians have to balance two things- respecting the parents’ decision and protecting the health of the child,” said Doug Opel, MD, MPH, bioethicist at Seattle Children’s Research Institute and a University of Washington acting assistant professor of pediatrics. “This is a difficult and important discussion, and what we found was that most pediatricians are comfortable being flexible with the immunization schedule when parents ask for this flexibility.”

The group of 209 pediatricians included in the study were least willing to revise the schedule for three vaccinations: diphtheria-tetanus toxoids-acellular pertussis vaccine (DTaP), Haemophilus influenzae type b vaccine (Hib) and pneumococcal conjugate vaccine (PCV). This suggests physicians want to prioritize immunizations that protect against some of the most common and most dangerous diseases which may occur during infancy and early childhood. Skipping the DTaP vaccine, for example, could lead to pertussis, also known as whooping cough. Pertussis is still common in the U.S. with frequent outbreaks. The Hib and PCV vaccines protect against infections like meningitis and pneumonia.

“The study demonstrates the need for more research on the use of alternative immunization schedules and the safety, efficacy and consequences of delaying immunizations,” said Dr. Opel. Seattle Children’s Research Institute will continue to study this topic to better understand the effect of childhood immunization schedules on individuals and public health.

Dr. Opel’s co-authors were: Aaron Wightman, MD, Seattle Children’s Research Institute and University of Washington; Edgar Marcuse, MD, MPH, Seattle Children’s Research Institute and University of Washington and James Taylor, MD, University of Washington.

Supporting Materials:

“Washington State Pediatricians’ Attitudes Toward Alternative Childhood Immunization Schedules,” study in Pediatrics:
Dr. Opel talks about alternative vaccination schedules and the study’s findings with Wendy Sue Swanson, MD, MBE, FAAP, on the Seattle Mama Doc blog:
Press Release: Child Health Leaders announce launch of Vax Northwest Partnership:

About Seattle Children’s Research Institute
At the forefront of pediatric medical research, Seattle Children’s Research Institute is setting new standards in pediatric care and finding new cures for childhood diseases. Internationally recognized scientists and physicians at the Research Institute are advancing new discoveries in cancer, genetics, immunology, pathology, infectious disease, injury prevention and bioethics. With Seattle Children’s Hospital and Seattle Children’s Hospital Foundation, the Research Institute brings together the best minds in pediatric research to provide patients with the best care possible. Children’s serves as the primary teaching, clinical and research site for the Department of Pediatrics at the University of Washington School of Medicine, which consistently ranks as one of the best pediatric departments in the country. For more information visit

Mary Guiden | EurekAlert!
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