Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study finds evidence of increased lung cancer risk among tuberculosis patients

03.01.2011
China Medical University study shows higher incidence of cancer in those who have had tuberculosis

Although a clear association of tuberculosis with lung cancer remains to be established, a new study published in the January issue of the Journal of Thoracic Oncology provides compelling evidence of increased lung cancer risk among people with tuberculosis.

Researchers at China Medical University and Hospital in Taiwan randomly selected 1 million patients covered under the country's National Health Insurance (NHI) program. All patients aged 20 years and older with a new diagnosis of tuberculosis between 1998 and 2000 were identified as the exposed cohort and all people without tuberculosis history were the non-exposed cohort. Patients with any cancer diagnosis were excluded to ensure that all participants were cancer-free at the start of both cohorts. Overall, 716,872 adults were eligible for the analysis - 4,480 in the tuberculosis cohort and 712,392 in the non-tuberculosis cohort.

Both groups were followed from 2001 through 2007. Results showed that patients with tuberculosis were 10.9 times more likely than non-tuberculosis patients to develop lung cancer (26.3 versus 2.41 per 10,000 person-years). Mortality was also much higher in the patients with tuberculosis than in the non-tuberculosis patients (51.1 versus 8.2 per 10,000 person-years).

"Tuberculosis is a very common chronic disease worldwide; people in the developing and undeveloped areas suffer with it mostly," said Dr. Chih-Yi Chen, one of the researchers. "It is well known that lung cancer is causally associated with smoking. Less attention has been focused on whether people with tuberculosis are also at higher risk of developing lung cancer. With the universal health insurance claims data of Taiwan, we identified 4,480 patients with tuberculosis from a group of 716,872 people and followed them for eight years or longer. The incidence of lung cancer in these tuberculosis patients was 11 times greater than people without tuberculosis. The risk of lung cancer may increase further to almost 16 times greater if patients with tuberculosis also suffer from chronic obstructive pulmonary disease. This study suggests that it is also important to watch out for lung cancer prevention in the campaign against tuberculosis."

The research was supported by the National Science Council, Executive Yuan, Taiwan; the Department of Health Clinical Trial and Research Center of Excellence; China Medical University Hospital; and Taiwan Department of Health, China Medical University Hospital Cancer Research of Excellence.

About the Journal of Thoracic Oncology:

The Journal of Thoracic Oncology (JTO) is the official monthly journal of the International Association for the Study of Lung Cancer (IASLC). It is a prized resource for medical specialists and scientists who focus on the detection, prevention, diagnosis and treatment of lung cancer. It emphasizes a multidisciplinary approach, including original research (clinical trials and translational or basic research), reviews and opinion pieces.

To find out more about the JTO please visit journals.lww.com. To learn more about the IASLC please visit iaslc.org.

Renée McGaw | EurekAlert!
Further information:
http://www.ucdenver.edu

Further reports about: Cancer IASLC Medical Wellness Oncology Thoracic health services lung cancer

More articles from Studies and Analyses:

nachricht Amputees can learn to control a robotic arm with their minds
28.11.2017 | University of Chicago Medical Center

nachricht The importance of biodiversity in forests could increase due to climate change
17.11.2017 | Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv) Halle-Jena-Leipzig

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>