Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study finds decreased life expectancy for multiple sclerosis patients

22.01.2014
The first large scale study in the U.S. on the mortality of patients with multiple sclerosis (MS) has been published and provides new information about the life expectancy of people with the disease. The study appears in the journal Multiple Sclerosis and Related Disorders.

David Kaufman, ScD, of the Slone Epidemiology Center at Boston University, is the lead author. The work is the result of a collaboration between the investigators at BU and their colleagues at University of California San Francisco, the University of Alabama, Heinrich Heine University in Düsseldorf, Care-Safe LLC, a consulting firm and the sponsor of the research, Bayer HealthCare Pharmaceuticals.

MS is a chronic disease of the central nervous system which progresses into a degenerative phase in the majority of affected patients. There are 250,000-350,000 patients with MS in the United States, giving an overall prevalence of roughly one in 1,000.

The investigators used health insurance claims data to identify a series of patients with MS and a comparison group of individuals from the same health plans who did not have MS. A total of 30,402 MS patients and 89,818 non-MS subjects who were in the OptumInsight Research (OIR) database from 1996-2009 were included in the study. Data on deaths was obtained from government databases of death records.

Annual mortality rates were 899/100,000 in MS patients and 446/100,000 in comparators. The median lifespan was 6 years less among the MS patients than among the non-MS group. "Our findings are consistent with what has been reported elsewhere in the world," explained Kaufman. "While the results apply only to the commercially insured U.S. population, that group represents more than two-thirds of individuals under age 65, and this is the first time an MS survival disadvantage has been shown in this country."

While early mortality due to MS is relatively rare, the new data confirm that compared to the general population, MS patients in the US do experience a decrease in life expectancy. Most of the information on survival patterns in MS has come from Europe, where populations, risk factors and medical practice may be different than in the U.S.

With the large number of MS patients in the U.S., the lack of data represented a significant knowledge gap. Future studies with longer follow-up periods can provide important information about how the introduction of anti-MS drugs in the 1990s has impacted survival in MS.

Gina DiGravio | EurekAlert!
Further information:
http://www.bmc.org

Further reports about: chronic disease multiple sclerosis risk factor

More articles from Studies and Analyses:

nachricht The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung

nachricht A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>