"Eight weeks on a Westernized high fat high cholesterol diet causes developmental neuroinflammation in middle-aged rats that can be reversed by an interleukin-1 receptor antagonist" said Dr. John Sladek, professor of neurology and pediatrics at the University of Colorado School of Medicine. "It will be interesting to see if the interleukin-1 receptor antagonist is still effective with a long term Westernized diet and whether this can be translated to humans."Contact: Dr. Linnea Freeman, Department of Neurosciences, Basic Science Building, Suite 411, 173 Ashley Ave. Medical University of South Carolina, Charleston, SC, 29425
Citation: Freeman, L. R.; Small, B. J.; Bickford, P. C.; Umphlet, C.; Granholm, A. C. A High Fat/High Cholesterol Diet Inhibits Growth Of Fetal Hippocampal Transplants Via Increased Inflammation. Cell Transplant. 20(10):1499-114; 2011.
The Coeditor-in-chief's for CELL TRANSPLANTATION are at the Center for Neuropsychiatry, China Medical University Hospital, TaiChung, Taiwan, and the Diabetes Research Institute, University of Miami Miller School of Medicine.
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