“We often think of Parkinson’s disease as being a disorder of motor function,” says Douglas Munoz, director of the Queen's Centre for Neuroscience Studies and a Canada Research Chair in Neuroscience. “But the issue is that the same circuit can affect more cognitive functions like planning and decision-making.”
The researchers conducted an experiment using a sample of Parkinson’s patients and a control group. When asked to look at a light when it came on, people with Parkinson’s responded with greater accuracy than people without the disease. But when asked to change that behavior – to look away from the light, for instance – Parkinson’s patients struggled. Even when asked to simply prepare to change their behaviour, people with the disease found it incredibly difficult to adjust their plans.
PhD student Ian Cameron, lead author of the study, says the findings are significant because they highlight how biased Parkinson’s patients are towards performing an automated response. It also suggests that medications currently prescribed to treat the symptoms of the disease that affect motor functioning could further upset a patient’s cognitive balance.
Mr. Cameron is now conducting functional brain imaging in Parkinson’s patients to determine which parts of the brain are affected by medications currently used to treat the symptoms of the disease.
The findings were recently published in Neuropsychologia, an international interdisciplinary journal of cognitive and behavioural neuroscience.
Kristyn Wallace | EurekAlert!
Do microplastics harbour additional risks by colonization with harmful bacteria?
05.04.2018 | Leibniz-Institut für Ostseeforschung Warnemünde
Rutgers-led innovation could spur faster, cheaper, nano-based manufacturing
14.02.2018 | Rutgers University
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...
13.04.2018 | Event News
12.04.2018 | Event News
09.04.2018 | Event News
20.04.2018 | Physics and Astronomy
20.04.2018 | Interdisciplinary Research
20.04.2018 | Physics and Astronomy