Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


New Study Explores the Relationship between Preterm Birth and Autism Spectrum Disorder

Recent studies have suggested that autism spectrum disorder (ASD) may be more prevalent among children born very prematurely.

The early symptoms of ASD are also associated with other conditions related to preterm births, such as cerebral palsy, which can make it difficult to correctly screen children for ASD.

Because of this, researchers have begun to explore the relationship between preterm birth, cognitive and developmental impairments, and ASD. Two articles soon to be published in The Journal of Pediatrics explore this possible correlation between preterm birth and ASD.

Dr. Karl Kuban and colleagues from Boston University, Wake Forest University, and Harvard University studied 988 children born between 2002 and 2004 who participated in the ELGAN (Extremely Low Gestational Age Newborn) study, a large, multi-center study that enrolled more than 1500 infants born at least three months prematurely. They wanted to explore whether children born preterm are more likely to screen positive on the Modified Checklist for Autism in Toddlers (M-CHAT), a survey administered to a caregiver regarding a child’s behavior. Pediatricians typically wait to formally diagnose ASD until after a child’s third birthday. In this study, however, the caregivers of the infants completed the M-CHAT when the children were 24 months of age. The researchers found that 21% of the preterm children screened positive for ASD.

Dr. Kuban and his colleagues were also interested in learning whether a child born prematurely who had motor, visual, hearing, or cognitive impairments was more likely to screen positive on the M-CHAT. Of the 988 children, 26% had cognitive impairments, 11% had cerebral palsy, 3% had visual impairments, and 2% had hearing impairments. They also observed that nearly half of the children with cerebral palsy and more than two-thirds of the children with visual or hearing impairments screened positive. According to Dr. Kuban, “Children who are born more than three months premature appear to be twice as likely to screen positive on the M-CHAT.” He notes, however, that the percentage of children who screened positive for ASD dropped to 10% when the variables of cognitive, visual, hearing, and motor impairments were removed.

In a related editorial, Dr. Neil Marlow and Dr. Samantha Johnson of University College London stress that because early identification leads to early treatment of children with ASD, screening tests are designed to over-identify children at risk. They suggest that useful knowledge may be gained by following the children as they mature to determine how many of those who initially screened positive actually develop ASD. Dr. Marlow notes that the study is valuable because “it raises our awareness of the difficulties in interpreting screening results.” He cautions that further research is needed before conclusions can be drawn about the direct correlation between preterm birth and ASD.

Brigid Huey | alfa
Further information:

More articles from Studies and Analyses:

nachricht Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung

nachricht High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>