The researchers examined 13 studies published between 1918 and 1920. During this time, many scientists erroneously believed that influenza was caused by bacteria, not a virus. As a result, researchers began performing and publishing results from clinical trials testing bacterial vaccines designed to prevent the flu. In their new study, Dr. Morens and his colleagues used modern statistical and evaluation methods to re-analyze the vaccine effectiveness data from these old studies in an attempt to correct for any statistical biases in the original analysis.
In addition to confirming the importance of bacterial infections associated with the 1918 influenza pandemic, the new analysis suggests that the use of bacterial vaccines containing S. pneumoniae could reduce pneumonia rates and deaths in modern influenza pandemics as well. During the 2009-2010 H1N1 influenza pandemic, the authors write, autopsy results implicated bacterial infections in 29 to 55 percent of deaths. In light of this study, the authors recommend more research into the use of bacterial vaccines to prevent illness and death associated with influenza.
ARTICLE: Y-W Chien et al. Efficacy of bacterial vaccines in preventing pneumonia and death during the 1918 influenza pandemic. Journal of Infectious Diseases. DOI: 10.1086/657144 (2010).
WHO: David M. Morens, M.D., Senior Advisor to the Director, NIAID, is available to comment on this article.
CONTACT: To schedule interviews, please contact Nalini Padmanabhan, 301-402-1663, email@example.com.
More information about NIAID research on flu is available at the NIAID Influenza Web portal (http://www.niaid.nih.gov/topics/flu/Pages/default.aspx).
NIAID conducts and supports research—at NIH, throughout the United States, and worldwide—to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at http://www.niaid.nih.gov.
The National Institutes of Health (NIH)—The Nation's Medical Research Agency—includes 27 Institutes and Centers and is a component of the U. S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments and cures for both common and rare diseases, For more information about NIH and its programs, visit http://www.nih.gov.
Nalini Padmanabhan | EurekAlert!
Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung
Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
Researchers from the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science, the Italian Space Agency (ASI), and the Instituto Geofisico--Escuela Politecnica Nacional (IGEPN) of Ecuador, showed an increasing volcanic danger on Cotopaxi in Ecuador using a powerful technique known as Interferometric Synthetic Aperture Radar (InSAR).
The Andes region in which Cotopaxi volcano is located is known to contain some of the world's most serious volcanic hazard. A mid- to large-size eruption has...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
16.08.2017 | Physics and Astronomy
16.08.2017 | Materials Sciences
16.08.2017 | Interdisciplinary Research