Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Spontaneous smoking cessation may be an early symptom of lung cancer, research suggests

01.03.2011
48 percent of patients in study quit before diagnosis, most before onset of symptoms

Many longtime smokers quit spontaneously with little effort shortly before their lung cancer is diagnosed, leading some researchers to speculate that sudden cessation may be a symptom of lung cancer.

Most patients who quit did so before noticing any symptoms of cancer, according to the study, which was published in the March issue of the Journal of Thoracic Oncology (JTO), the official monthly journal of the International Association for the Study of Lung Cancer (IASLC).

"It is widely known that many lung cancer patients have stopped smoking before diagnosis," said Dr. Barbara Campling, professor in the Department of Medical Oncology at Thomas Jefferson University in Philadelphia. "This observation is often dismissed, by saying that these patients must have quit because of symptoms of their cancer. However, we found that the majority of lung cancer patients who stopped smoking before diagnosis quit before the onset of symptoms. Furthermore, they often quit with no difficulty, despite multiple previous unsuccessful quit attempts. This has led us to speculate that, in some cases, spontaneous smoking cessation may be an early symptom of lung cancer."

Researchers interviewed 115 lung cancer patients from the Philadelphia Veterans Affairs Medical Center, all of whom had been smokers. Fifty-five (48%) had quit smoking before diagnosis, and only six of those (11%) had experienced symptoms of lung cancer by the time they quit. Patients with lung cancer who quit were as dependent on nicotine, when their smoking was at its highest point, as those who continued to smoke. Yet 31% reported quitting with no difficulty.

For comparison, researchers also interviewed patients with prostate cancer and those who had suffered a heart attack. They found that the median interval between quitting smoking and lung cancer diagnosis was 2.7 years. This compared with 24.3 years for prostate cancer and 10 years for a heart attack.

Researchers speculated that spontaneous smoking cessation may be a presenting symptom of lung cancer, possibly caused by tumor secretion of a substance interfering with nicotine addiction.

The results should not encourage smokers to continue smoking, Campling said.

"There is a danger that this study could be misinterpreted as suggesting that heavy smokers should continue smoking," Campling said. "We emphasize that all smokers must be strongly encouraged to stop."

Alternate media contact:
Steve Graff
Thomas Jefferson University
215-955-5291
Stephen.graff@jefferson.edu
The research was supported by a grant from the Veterans Affairs Healthcare Network Competitive Pilot Project.

About the Journal of Thoracic Oncology:

The Journal of Thoracic Oncology (JTO) is the official monthly journal of the International Association for the Study of Lung Cancer (IASLC). It is a prized resource for medical specialists and scientists who focus on the detection, prevention, diagnosis and treatment of lung cancer. It emphasizes a multidisciplinary approach, including original research (clinical trials and translational or basic research), reviews and opinion pieces.

To find out more about the JTO please visit journals.lww.com. To learn more about the IASLC please visit iaslc.org.

Renée McGaw | EurekAlert!
Further information:
http://www.ucdenver.edu

More articles from Studies and Analyses:

nachricht Amputees can learn to control a robotic arm with their minds
28.11.2017 | University of Chicago Medical Center

nachricht The importance of biodiversity in forests could increase due to climate change
17.11.2017 | Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv) Halle-Jena-Leipzig

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>