Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Screening has prevented half a million colorectal cancers

03.06.2014

An estimated half a million cancers were prevented by colorectal cancer screening in the United States from 1976 to 2009, report researchers from the Cancer Outcomes, Public Policy, and Effectiveness Research Center at Yale Cancer Center

An estimated half a million cancers were prevented by colorectal cancer screening in the United States from 1976 to 2009, report researchers from the Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center at Yale Cancer Center. Their study appears in the journal Cancer.

During this more than 30-year time span, as increasing numbers of men and women underwent cancer screening tests — including fecal occult blood testing, sigmoidoscopies, and colonoscopies — colorectal cancer rates declined significantly, the researchers found.

The Yale COPPER team studied the colorectal cancer incidence data from the National Cancer Institute's Surveillance, Epidemiology, and End Results database, along with its Cancer Trends Progress Report. Researchers found that the incidence of late-stage cancer decreased from 118 cases per 100,000 people over the age of 50, to 74 cases per 100,000.

They also found that the incidence of early-stage cancers declined from 77 to 67 cases per 100,000 people over the age of 50, during a period where cancer screening increased from 34.8% to 66.1%. After adjusting for trends in cancer incidence, the authors calculated that there was a reduction of 550,000 cancers during this period of increasing screening.

"These numbers represent real patients and families who have been spared the trauma of a cancer diagnosis and treatment," said the study's senior author, James Yu, M.D., assistant professor of therapeutic radiology at Yale School of Medicine. "Colorectal cancer screening is one of the major successes in cancer care."

These findings are particularly significant in light of recent controversy surrounding mammography screening for breast cancer, and suggestions that it may result in false positive diagnoses and overtreatment, note the researchers. "The efficacy of colorectal cancer screening is important to highlight, especially at a time when there has been a national discussion about screening for other types of cancer," said Cary Gross, M.D., a co-author on the study and director of the Yale COPPER Center.

###

Other authors are Daniel Yang, Cary Gross, M.D., and Pamela Soulos of Yale School of Medicine and the Cancer Outcomes, Public Policy, and Effectiveness Research Center at Yale.

Gross received funding from Medtronic Inc. and Johnson & Johnson as a collaborator on the Yale University Open Data Access Project, which is facilitating the sharing and objective analysis of clinical trial data. Yu is supported by Clinical and Translational Science Award KL2 TR000140 from the National Center for Advancing Translational Science, a component of the National Institutes of Health (NIH), and by the NIH Roadmap for Medical Research. Disclosure: Gross and Yu report funding from 21st-Century Oncology LLC.

Helen Dodson | Eurek Alert!
Further information:
http://www.yale.edu

More articles from Studies and Analyses:

nachricht The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

Im Focus: Fast, convenient & standardized: New lab innovation for automated tissue engineering & drug

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...

Im Focus: Silencing bacteria

HZI researchers pave the way for new agents that render hospital pathogens mute

Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...

Im Focus: Artificial Enzymes for Hydrogen Conversion

Scientists from the MPI for Chemical Energy Conversion report in the first issue of the new journal JOULE.

Cell Press has just released the first issue of Joule, a new journal dedicated to sustainable energy research. In this issue James Birrell, Olaf Rüdiger,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

New quantum phenomena in graphene superlattices

19.09.2017 | Physics and Astronomy

A simple additive to improve film quality

19.09.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>