Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Roadmap to 25 percent reduction in premature deaths From RHD in the under 25s by 2025 published

09.04.2013
World Heart Federation position statement published online in Nature Reviews Cardiology
The World Heart Federation has published a new position statement outlining the five key strategic targets required to meet its strategic goal for rheumatic heart disease (RHD) – a 25% reduction in premature deaths from rheumatic fever (RF) and RHD among individuals aged
RHD remains the most common cardiovascular disease in young people aged
Conservative estimates indicate that there are between 15.6 and 19.6 million existing cases of RHD and its been estimated that there are around 252,000 new cases each year. Moreover, an estimated 233,000 to 468,164 individuals die from RHD each year, and hundreds of thousands of people are disabled by this disease and its long-term complications.

"RF and RHD are neglected diseases that require immediate attention," Professor Bongani Mayosi, Groote Schuur Hospital and University of Cape Town, South Africa; and Chair of the World Heart Federation Working Group on Rheumatic Fever and Rheumatic Heart Disease. "This position paper will form the platform for a detailed operational plan to address the barriers to RF and RHD control. The operational plan will be founded on science, research and quantifiable progress indicators to impact positively on millions of individuals with RHD."

A number of barriers have been identified that are currently preventing the control of RF and RHD.

Neglect of RF and RHD – there is a relative lack of engagement in disease control by governments, civil society, patient advocates and funding agencies.
Scarcity of data and scientific knowledge – Contemporary data is scarce. The current global figure for RHD mortality is speculative and likely to be a gross underestimate. But, descriptive and prognostic epidemiological data outlining disease prevalence, mortality and morbidity are critical for developing realistic targets and key performance indicators towards disease control.

Research – Global research priorities for RF and RHD have been identified but there is a great need for resource allocation to conduct robust research into these priorities.

Vaccines – a GAS vaccine is required for effective population-level primary prevention of RF is needed. GAS vaccine development and human testing has been underway for nearly a century with fluctuating enthusiasm. Few pharmaceutical companies have active internal programmes.

Access to health care – Barriers exist to optimal primary, secondary and tertiary (medical and surgical care). Many patients around the world do not have access to the treatments they need at all stages of management.

The primary aim of this position paper is to serve as a guide on how to achieve the objective of controlling RHD and eliminating RF. Five strategic targets have been identified:

Comprehensive register-based control programmes
Global access to benzathine penicillin G
Identification and development of public figures as 'RHD champions'
Expansion of RHD training hubs
Support for vaccine development
Moreover, this document is intended to provide the foundation for governments, civil society, patient advocates, clinicians, researchers and funding agencies to develop partnerships and unify global efforts to control RF and RHD.
About RHD

RHD is a chronic heart condition caused by rheumatic fever that can be prevented and controlled. Rheumatic fever is caused by a preceding group A streptococcal (strep) throat infection. Treating strep throat with antibiotics can prevent rheumatic fever. Moreover, regular antibiotics (usually by injections every three to four weeks) can prevent patients with rheumatic fever from contracting further strep infections and causing progression of valve damage.
About the World Heart Federation

The World Heart Federation is dedicated to leading the global fight against heart disease and stroke with a focus on low- and middle-income countries via a united community of more than 200 member organizations. With its members, the World Heart Federation works to build global commitment to addressing cardiovascular health at the policy level, generates and exchanges ideas, shares best practice, advances scientific knowledge and promotes knowledge transfer to tackle cardiovascular disease – the world's number one killer. It is a growing membership organization that brings together the strength of medical societies and heart foundations from more than 100 countries. Through our collective efforts we can help people all over the world to lead longer and better heart-healthy lives. For more information, please visit: http://www.worldheart.org; twitter.com/worldheartfed; facebook.com/worldheartfederation

Charanjit Jagait | EurekAlert!
Further information:
http://www.worldheart.org

More articles from Studies and Analyses:

nachricht Win-win strategies for climate and food security
02.10.2017 | International Institute for Applied Systems Analysis (IIASA)

nachricht The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Salmonella as a tumour medication

HZI researchers developed a bacterial strain that can be used in cancer therapy

Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

3rd Symposium on Driving Simulation

23.10.2017 | Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

 
Latest News

Microfluidics probe 'cholesterol' of the oil industry

23.10.2017 | Life Sciences

Gamma rays will reach beyond the limits of light

23.10.2017 | Physics and Astronomy

The end of pneumonia? New vaccine offers hope

23.10.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>