Venous thromboembolism (VTE) is the third most common type of cardiovascular disease after coronary heart disease and stroke. Researchers at the Centre for Primary Health Care Research in Malmö have mapped the significance of hereditary factors for venous thromboembolism in the entire Swedish population by studying the risk of VTE in children of parents with VTE compared with the children of parents who have not had VTE.
“Previously, hereditary factors for venous thromboembolism have only been studied on a small scale. We based our study on the entire Swedish population”, says Bengt Zöller, researcher at the Centre for Primary Health Care Research, Malmö. Using the national multi-generation register and hospital discharge register, the researchers examined the risk of being affected if one or both parents have had venous thromboembolism. During the period 1987 to 2007, a total of 45 362 people suffered from venous thromboembolism, of whom 4 865 had hereditary VTE and thus a higher risk of being affected.
The study shows that hereditary factors are of most significance at a younger age – between 10 and 50 – and occur in both men and women. The highest relative risk was seen in the 10–19 age group. After the age of 50, other factors appear to play a greater role than hereditariness. Blood clots in the very young, under the age of 10, are rare, but strangely enough, hereditary factors do not appear to be the most significant in this age group. The highest risk occurs if both parents have had venous thromboembolism.
“The findings are an important guide to the importance of hereditary factors for VTE. In conclusion, a parental history of venous thromboembolism is an important risk factor that should be included in the clinical medical history and examination”, says Bengt Zöller.
Article: Zöller, B., Li, X., Sundquist, J., Sundquist, K. Parental history and venous thromboembolism: a nationwide study of age-specific and sex-specific familial risks in Sweden. J Thromb Haemost. 2011;9:64-70.
Reviewed by: Ragni, M. V. Coming of Age and Thrombosis: It’s All in the Family. The Hematologist 2011;8:9.http://www.hematology.org/Publications/Hematologist/Issues/6635.aspx
The Centre for Primary Health Care Research in Malmö is a collaboration between Lund University and Region Skåne.
Contact: Bengt Zöller, MD, PhD, +46 40 391954, firstname.lastname@example.org
Megan Grindlay | idw
The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung
A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences