Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Risk of blood clots in veins hereditary

30.05.2011
In a nationwide study, researchers at the Centre for Primary Health Care Research in Malmö, Sweden, have mapped the significance of hereditary factors in venous thromboembolism.

Venous thromboembolism (VTE) is the third most common type of cardiovascular disease after coronary heart disease and stroke. Researchers at the Centre for Primary Health Care Research in Malmö have mapped the significance of hereditary factors for venous thromboembolism in the entire Swedish population by studying the risk of VTE in children of parents with VTE compared with the children of parents who have not had VTE.

“Previously, hereditary factors for venous thromboembolism have only been studied on a small scale. We based our study on the entire Swedish population”, says Bengt Zöller, researcher at the Centre for Primary Health Care Research, Malmö. Using the national multi-generation register and hospital discharge register, the researchers examined the risk of being affected if one or both parents have had venous thromboembolism. During the period 1987 to 2007, a total of 45 362 people suffered from venous thromboembolism, of whom 4 865 had hereditary VTE and thus a higher risk of being affected.

The study shows that hereditary factors are of most significance at a younger age – between 10 and 50 – and occur in both men and women. The highest relative risk was seen in the 10–19 age group. After the age of 50, other factors appear to play a greater role than hereditariness. Blood clots in the very young, under the age of 10, are rare, but strangely enough, hereditary factors do not appear to be the most significant in this age group. The highest risk occurs if both parents have had venous thromboembolism.

“The findings are an important guide to the importance of hereditary factors for VTE. In conclusion, a parental history of venous thromboembolism is an important risk factor that should be included in the clinical medical history and examination”, says Bengt Zöller.

Article: Zöller, B., Li, X., Sundquist, J., Sundquist, K. Parental history and venous thromboembolism: a nationwide study of age-specific and sex-specific familial risks in Sweden. J Thromb Haemost. 2011;9:64-70.

Reviewed by: Ragni, M. V. Coming of Age and Thrombosis: It’s All in the Family. The Hematologist 2011;8:9.http://www.hematology.org/Publications/Hematologist/Issues/6635.aspx

The Centre for Primary Health Care Research in Malmö is a collaboration between Lund University and Region Skåne.

Contact: Bengt Zöller, MD, PhD, +46 40 391954, bengt.zoller@med.lu.se

Megan Grindlay | idw
Further information:
http://www.vr.se
http://www.hematology.org/Publications/Hematologist/Issues/6635.aspx

More articles from Studies and Analyses:

nachricht New study from the University of Halle: How climate change alters plant growth
12.01.2018 | Martin-Luther-Universität Halle-Wittenberg

nachricht Disarray in the brain
18.12.2017 | Universität zu Lübeck

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Meteoritic stardust unlocks timing of supernova dust formation

19.01.2018 | Physics and Astronomy

Method uses DNA, nanoparticles and lithography to make optically active structures

19.01.2018 | Materials Sciences

More genes are active in high-performance maize

19.01.2018 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>