Dr. Laurie Lawrence, animal science professor at the University of Kentucky, said the amount of selenium in soil and forages varies across the United States. She said that they wanted to know whether horses grazing pasture that was marginal in selenium would react differently to vaccines, compared with horses that were supplemented with additional dietary selenium.
Mieke Brummer, PhD student working with the University of Kentucky and Alltech, said she was interested in the effects of selenium on the immune system, specifically the cell-mediated component of the immune system. The cell-mediated component is responsible for the activation of immune cells. These immune cells can directly attack foreign antigens.
In this experiment, twenty-eight adult horses were divided by age and sex. The horses were then randomly assigned to a dietary selenium treatment. Brummer said the first phase lasted 35-weeks. During the first phase, the researchers were aiming to deplete the selenium in the horses that were assigned to the low diet.
In the next 29-weeks, some the horses that were assigned to low treatments were given additional dietary selenium supplements. Brummer said the horses were either given organic or inorganic selenium supplements. During the last 7 weeks, the horses were given vaccinations. The researchers collected blood samples to evaluate immune response during this time.
Brummer said that the evaluation of vaccination response was not effective. She said other measures of cell-mediated immunity suggested that cell-mediated immune function was suppressed in the horses with low selenium consumption. She said antibody production was unaffected.
“It is important for horse owners to read feed labels so they can avoid both over-supplementation and under-supplementation of all classes of horses,” Lawrence said.
Lawrence said the horses were not performing strenuous exercises in this study. She said the results could have been different if the horses were under performance stress. She said additional research would need to be conducted to study the interaction between selenium, antioxidant and immune response in exercising horses.
Brummer said this study was funded by the Alltech-University of Kentucky Nutrigenomics Alliance.
This article is titled “The effect of selenium supplementation on vaccination response and immune function in adult horses.” It can be read in full at the journalofanimalscience.org.Scientific Contact:
Madeline McCurry-Schmidt | EurekAlert!
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy