Dr. Laurie Lawrence, animal science professor at the University of Kentucky, said the amount of selenium in soil and forages varies across the United States. She said that they wanted to know whether horses grazing pasture that was marginal in selenium would react differently to vaccines, compared with horses that were supplemented with additional dietary selenium.
Mieke Brummer, PhD student working with the University of Kentucky and Alltech, said she was interested in the effects of selenium on the immune system, specifically the cell-mediated component of the immune system. The cell-mediated component is responsible for the activation of immune cells. These immune cells can directly attack foreign antigens.
In this experiment, twenty-eight adult horses were divided by age and sex. The horses were then randomly assigned to a dietary selenium treatment. Brummer said the first phase lasted 35-weeks. During the first phase, the researchers were aiming to deplete the selenium in the horses that were assigned to the low diet.
In the next 29-weeks, some the horses that were assigned to low treatments were given additional dietary selenium supplements. Brummer said the horses were either given organic or inorganic selenium supplements. During the last 7 weeks, the horses were given vaccinations. The researchers collected blood samples to evaluate immune response during this time.
Brummer said that the evaluation of vaccination response was not effective. She said other measures of cell-mediated immunity suggested that cell-mediated immune function was suppressed in the horses with low selenium consumption. She said antibody production was unaffected.
“It is important for horse owners to read feed labels so they can avoid both over-supplementation and under-supplementation of all classes of horses,” Lawrence said.
Lawrence said the horses were not performing strenuous exercises in this study. She said the results could have been different if the horses were under performance stress. She said additional research would need to be conducted to study the interaction between selenium, antioxidant and immune response in exercising horses.
Brummer said this study was funded by the Alltech-University of Kentucky Nutrigenomics Alliance.
This article is titled “The effect of selenium supplementation on vaccination response and immune function in adult horses.” It can be read in full at the journalofanimalscience.org.Scientific Contact:
Madeline McCurry-Schmidt | EurekAlert!
The importance of biodiversity in forests could increase due to climate change
17.11.2017 | Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv) Halle-Jena-Leipzig
Win-win strategies for climate and food security
02.10.2017 | International Institute for Applied Systems Analysis (IIASA)
High-precision measurement of the g-factor eleven times more precise than before / Results indicate a strong similarity between protons and antiprotons
The magnetic moment of an individual proton is inconceivably small, but can still be quantified. The basis for undertaking this measurement was laid over ten...
Heat from the friction of rocks caused by tidal forces could be the “engine” for the hydrothermal activity on Saturn's moon Enceladus. This presupposes that...
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
15.11.2017 | Event News
15.11.2017 | Event News
30.10.2017 | Event News
24.11.2017 | Physics and Astronomy
24.11.2017 | Health and Medicine
24.11.2017 | Earth Sciences