Coronary artery calcium is a strong predictor of future heart attacks with a nearly 10 fold increase in the risk of coronary heart disease (CHD) in patients with elevated CAC.
The article is based on research in 2,703 patients from the Family Heart Study, a government sponsored study of the relationship between potential risk factors and heart disease and is the first study to examine the relationship between adult height and CAC in a large population.
It suggests that taller adults tend to have lower levels of plaque, and thus, a lower risk of CHD. This relationship persisted even after accounting for standard cardiovascular risk factors such as age, smoking, high cholesterol, and diabetes. The full article can be found at: http://circimaging.ahajournals.org/content/early/2013/12/10/CIRCIMAGING.113.000681.abstract
"A potential link between height and CHD has been shown in several studies but the mechanism of this relationship has not been clear and our study suggests the relationship is mediated by plaque build up in the coronary arteries", said Michael Miedema, MD, MPH, from the Minneapolis Heart Institute Foundation. There may be as much as 30% lower risk of plaque build-up in the top quarter of tallest adults compared to the bottom quarter. These results had to be adjusted for gender, given the differences in height between men and women, but the relationship was consistent in both men and women."
Why taller individuals develop less plaque is not entirely clear.
"Some studies suggest that taller people have favorable changes in their blood pressure due their height but these changes are quite small and unlikely to be the sole cause of this relationship", Miedema stated. "It may be more likely that this relationship is mediated through a common link, such as childhood nutrition or other environmental factors during childhood, which may be determinants of both adult height as well as future coronary heart disease."
This report is presented on behalf of the investigators of the NHLBI Family Heart Study. Funding sources include National Heart, Lung, and Blood Institute cooperative agreement grants.About the Minneapolis Heart Institute Foundation
Scientific Innovation and Research – Publishing more than 120 peer-reviewed studies each year, MHIF is a recognized research leader in the broadest range of cardiovascular medicine. Each year, cardiologists and hospitals around the world adopt MHIF protocols to save lives and improve patient care.
Education and Outreach – Research shows that modifying specific health behaviors can significantly reduce the risk of developing heart disease. Through community programs, screenings and presentations, MHIF educates people of all walks of life about heart health. The goal of the Foundation's community outreach is to increase personal awareness of risk factors and provide the tools necessary to help people pursue heart- healthy lifestyles.About the Minneapolis Heart Institute®
Steve Goodyear | EurekAlert!
Rutgers-led innovation could spur faster, cheaper, nano-based manufacturing
14.02.2018 | Rutgers University
New study from the University of Halle: How climate change alters plant growth
12.01.2018 | Martin-Luther-Universität Halle-Wittenberg
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
21.02.2018 | Materials Sciences
21.02.2018 | Health and Medicine
21.02.2018 | Physics and Astronomy