Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Neandertals, humans share key changes to 'language gene'

22.10.2007
A new study published online on October 18th in Current Biology reveals that adaptive changes in a human gene involved in speech and language were shared by our closest extinct relatives, the Neandertals.

The finding reveals that the human form of the gene arose much earlier than scientists had estimated previously. It also raises the possibility that Neandertals possessed some of the prerequisites for language.

The gene, which is called FOXP2, is the only one known to date to play a role in speech and language, according to the researchers. People who carry an abnormal copy of the FOXP2 gene have speech and language problems.

“From the point of view of this gene, there is no reason to think that Neandertals would not have had the ability for language,” said Johannes Krause of the Max Planck Institute for Evolutionary Anthropology. He noted, however, that many as-yet-unknown genes might underlie the capacity for language. Once found, those would have to be examined in Neandertals as well.

Previous analyses indicated that a very recent rise in the human FOXP2 variant had occurred as a result of strong selection, less than 200,000 years ago, added Svante Pääbo, also of the Max Planck Institute. “Because we know that Neandertal and modern human populations diverged more than 300,000 years ago, we would have guessed that these changes in FOXP2 would have happened after we separated from Neandertals,” Pääbo said, noting that the human version of FOXP2 differs from that of chimps in two places.

The researchers extracted DNA from Neandertal fossils collected in a cave in northern Spain. They exhumed the bones under sterile conditions and froze them before transporting them to the laboratory. They then extracted DNA and sequenced the Neandertal FOXP2 gene, revealing that it was identical to the version found in modern humans. To ensure that the Neandertal DNA samples hadn’t been contaminated with human DNA, they also sequenced parts of their Y chromosome, which was found to be distinct from that of men today.

In addition to its potential implications for the acquisition of language, the study also marks the first time a specific nuclear gene has been retrieved from Neandertals—opening the door to other breakthroughs in scientists’ understanding of human and Neandertal evolution, the researchers said.

“The current results show that the Neandertals carried a FOXP2 protein that was identical to that of present-day humans in the only two positions that differ between human and chimpanzee,” the researchers concluded. “Leaving out the unlikely scenario of gene flow [between the two lineages], this establishes that these changes were present in the common ancestor of modern humans and Neandertals.

The date of the emergence of these genetic changes therefore must be older than that estimated with only extant human diversity data, thus demonstrating the utility of direct evidence from Neandertal DNA sequences for understanding recent modern human evolution."

Nancy Wampler | EurekAlert!
Further information:
http://www.current-biology.com

More articles from Studies and Analyses:

nachricht Multi-year study finds 'hotspots' of ammonia over world's major agricultural areas
17.03.2017 | University of Maryland

nachricht Diabetes Drug May Improve Bone Fat-induced Defects of Fracture Healing
17.03.2017 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>