Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Neandertals, humans share key changes to 'language gene'

22.10.2007
A new study published online on October 18th in Current Biology reveals that adaptive changes in a human gene involved in speech and language were shared by our closest extinct relatives, the Neandertals.

The finding reveals that the human form of the gene arose much earlier than scientists had estimated previously. It also raises the possibility that Neandertals possessed some of the prerequisites for language.

The gene, which is called FOXP2, is the only one known to date to play a role in speech and language, according to the researchers. People who carry an abnormal copy of the FOXP2 gene have speech and language problems.

“From the point of view of this gene, there is no reason to think that Neandertals would not have had the ability for language,” said Johannes Krause of the Max Planck Institute for Evolutionary Anthropology. He noted, however, that many as-yet-unknown genes might underlie the capacity for language. Once found, those would have to be examined in Neandertals as well.

Previous analyses indicated that a very recent rise in the human FOXP2 variant had occurred as a result of strong selection, less than 200,000 years ago, added Svante Pääbo, also of the Max Planck Institute. “Because we know that Neandertal and modern human populations diverged more than 300,000 years ago, we would have guessed that these changes in FOXP2 would have happened after we separated from Neandertals,” Pääbo said, noting that the human version of FOXP2 differs from that of chimps in two places.

The researchers extracted DNA from Neandertal fossils collected in a cave in northern Spain. They exhumed the bones under sterile conditions and froze them before transporting them to the laboratory. They then extracted DNA and sequenced the Neandertal FOXP2 gene, revealing that it was identical to the version found in modern humans. To ensure that the Neandertal DNA samples hadn’t been contaminated with human DNA, they also sequenced parts of their Y chromosome, which was found to be distinct from that of men today.

In addition to its potential implications for the acquisition of language, the study also marks the first time a specific nuclear gene has been retrieved from Neandertals—opening the door to other breakthroughs in scientists’ understanding of human and Neandertal evolution, the researchers said.

“The current results show that the Neandertals carried a FOXP2 protein that was identical to that of present-day humans in the only two positions that differ between human and chimpanzee,” the researchers concluded. “Leaving out the unlikely scenario of gene flow [between the two lineages], this establishes that these changes were present in the common ancestor of modern humans and Neandertals.

The date of the emergence of these genetic changes therefore must be older than that estimated with only extant human diversity data, thus demonstrating the utility of direct evidence from Neandertal DNA sequences for understanding recent modern human evolution."

Nancy Wampler | EurekAlert!
Further information:
http://www.current-biology.com

More articles from Studies and Analyses:

nachricht A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg

nachricht Urbanization to convert 300,000 km2 of prime croplands
27.12.2016 | Mercator Research Institute on Global Commons and Climate Change (MCC) gGmbH

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

Im Focus: Bacterial Pac Man molecule snaps at sugar

Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.

The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...

Im Focus: Newly proposed reference datasets improve weather satellite data quality

UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration

"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...

Im Focus: Repairing defects in fiber-reinforced plastics more efficiently

Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.

Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

Multiregional brain on a chip

16.01.2017 | Power and Electrical Engineering

New technology enables 5-D imaging in live animals, humans

16.01.2017 | Information Technology

Researchers develop environmentally friendly soy air filter

16.01.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>