The Human Papillomavirus (HPV) is considered the cause of one of the most important sexually transmitted diseases nowadays, and affects both men and women. HPV is so common in our society that only people who have never had sexual relations can be sure that they have not been exposed to this disease. However, as with other microbes, people infected do not necessarily develop the disease, because, in most cases, it only means the colonization. Only some of the people colonized will fall ill with different processes.
Nevertheless, the development of this disease might have serious consequences: It is probable that HPV is related to bladder cancer, according to a recent study carried out by the Department of Microbiology [http://www.ugr.es/~dptomic/] of the University of Granada, in collaboration with the Department of Biostatistics [http://www.ugr.es/~bioest/] and the Urology Service of San Cecilio Hospital.
Several previous studies point out the possibility that HPV might cause, in certain subjects, some types of cancer: cervical, anus, vulva, penis, oropharyngeal (the middle part of the throat behind the mouth including the back of the tongue, the soft palate, the side and back walls of the throat) and bladder cancer. The researchers from Granada have focused their study on bladder cancer and have found some evidence of the relationship between both diseases. Nevertheless, they warn that further research on this matter is needed, particularly in order rule out the assumption that this infection is only a viral colonization and does not cause cancer (that is to say, the tumor appeared before the tissue was infected by the virus).
Jose Gutiérrez Fernández, lecturer responsible for this study explains that, in order to draw this preliminary conclusion, 44 articles related to this matter written by experts from all around the world were analysed. “Our work consisted in a bibliographic review of the observational case studies published up to July 2005, in order to establish the degree of relationship found between bladder cancer and HPV infection”.
Standardization of methods
The study carried out at the UGR [http://www.ugr.es] points out that the relationship between these two diseases depends on the method used: these scientists found different results depending on whether the research was based on the person’s DNA or not. “Of the 44 studies reviewed, in 39 the presence of DNA was studied. In the other 7 studies the HPV infection was studied through antigen or antibody detection".
The great majority of these studies use PCR (Polymerase Chain Reaction) for the analysis. With this technique it is possible to duplicate as many times as desired a fragment of DNA in a test tube, and millions of identical molecules can be created from a single DNA molecule.
The relationship between HPV and bladder cancer might be due to the fact that the microorganism which generates the infection has DNA. Therefore, it acts directly on the cell nucleus and makes the cell cancerous. Moreover, the infection spreads quickly when healthy mucus comes into contact with infected mucus.
The research performed by the UGR [http://www.ugr.es] points out that there might be a relationship between Human Papillomavirus infection and the appearance of the tumor. However, Gutiérrez Fernández warns that “in order to draw a final conclusion, it is necessary to carry out a study with a sufficient number of cases and samples in which a combination of several microbiological techniques is applied to the same subject and sample”.
Antonio Marín Ruiz | alfa
Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung
High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences