Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New cell sample method can lead to better protection against cervical cancer

10.09.2007
A new way to examine cell changes in the cervix may mean that fewer women will develop cervical cancer. This is shown in a study from the Sahlgrenska Academy.

Women between the ages of 23 and 60 are regularly called in to submit cell samples. Participating in these check-ups has been shown to provide good protection against cervical cancer. But the test method is not entirely reliable. When a woman develops cervical cancer, the most common reason is that she did not take part in the check-up, but it happens that women who did participate nevertheless get cancer.

Researchers at the Sahlgrenska Academy have carried out a large-scale study comprising 13,484 women in the Göteborg area. Samples were taken at five different maternity clinics. The women were randomly selected to submit cell specimins using either the traditional method or a partially new method. With the new method, liquid-based cytology, the sampler mixes the cells in a fluid solution instead of smearing them on a glass slide. In the laboratory the solution is processed in a machine that produces a glass slide with a purer background that is easier to assess.

In the study, all cell changes found were examined in the same way, regardless of sample type. After the women had been examined using tissue biopsies taken by a gynecologist, between 40 and 60 percent more women with major changes were found in the group that had been sampled using liquid cell specimens. All changes of this degree of severity were then treated with a simple surgical procedure.

"If cell changes in a woman are missed, there are usually further chances of finding them, since these changes develop slowly. But the results of the study indicate that more cases of cancer can be prevented if we start using this more sensitive method," says Björn Strander, a doctoral student at the Sahgrenska Academy who is in charge of preventing cervical cancer at the Oncology Center, Västra Götaland Healthcare Region in western Sweden.

The study also showed that fewer samples had to be thrown out as unassessable, but that the proportion of women who were asked to undergo further examination based on some deviation in their cell specimen rose from 3.5 percent to 4.5 percent of those submitting samples.

¬"Now that we have acquired experience with the method, we see many advantages for the laboratory. The samples are easier to assess, and work goes faster. The remaining fluid can be used for other lab analyses, such as virus testing, which can be a valuable complement in the diagnosis. What's more, part of the diagnosis can be done automatically, a factor that will be important in the future," says Walter Ryd, head of the Cytology Laboratory at the Sahlgrenska University Hospital and leader of the study.

The study is now being published on the Web page of the international scientific journal Cancer Cytopathology.

Journal: Cancer Cytopathology
Title of article: Liquid-based cytology versus conventional Papanicolaou smear in an organized screening program: a prospective randomized study

Authors: Björn Strander, Agneta Andersson-Ellström, Ian Milsom, Thomas Rådberg, Walter Ryd

For more information, please contact:
Associate Professor Walter Ryd, phone: +46 (0)31-342 21 86; cell phone: +46 (0)70-85 00 08, e-mail: valter.ryd@vgregion.se

Doctoral student Björn Strander, Department of Clinical Sciences, cell phone: +46 (0)704-97 22 26, e-mail: bjorn.strander@oc.gu.se

Ulrika Lundin
Press officer
Sahlgrenska Academy at Göteborg University
Phone: +46 (0)31-786 38 69
Cell phone: +46 (0)70-775 88 51
e-mail: ulrika.lundin@sahlgrenska.gu.se

Ulrika Lundin | idw
Further information:
http://www.vr.se

More articles from Studies and Analyses:

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

nachricht Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

Im Focus: Quantum-physical Model System

Computer-assisted methods aid Heidelberg physicists in reproducing experiment with ultracold atoms

Two researchers at Heidelberg University have developed a model system that enables a better understanding of the processes in a quantum-physical experiment...

Im Focus: Glacier bacteria’s contribution to carbon cycling

Glaciers might seem rather inhospitable environments. However, they are home to a diverse and vibrant microbial community. It’s becoming increasingly clear that they play a bigger role in the carbon cycle than previously thought.

A new study, now published in the journal Nature Geoscience, shows how microbial communities in melting glaciers contribute to the Earth’s carbon cycle, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

New quantum liquid crystals may play role in future of computers

21.04.2017 | Physics and Astronomy

A promising target for kidney fibrosis

21.04.2017 | Health and Medicine

Light rays from a supernova bent by the curvature of space-time around a galaxy

21.04.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>