It is well known that tobacco consumption causes a respiratory disease called chronic obstructive pulmonary disease (COPD), characterized by formation of emphysema and progressive destruction of the lung.
When pulmonary vessels are altered in this disease, life expectancy of the patients worsens. It has not been possible to establish the cause, but it has been attributed to low oxygen concentration in the blood.
However, changes in the pulmonary vessels have also been found in COPD patients with normal oxygen concentrations. These abnormalities mainly consist of the thickening of the internal coat of pulmonary arteries, resulting in a decrease of the arterial lumen size.
The cellular and extracellular components that are involved in this enlargement are unknown.
A study published in this month’s European Respiratory Journal (ERJ) by Prof. J.A. Barbera of the Servei de Pneumologia Hospital Clinic in Barcelona, Spain, and colleagues was designed to characterize the changes occurring in pulmonary arteries of patients with mild COPD and in smokers who have not yet developed the disease.
The researchers found that the thickening of the wall is mainly due to the proliferation of smooth muscle cells with synthetic capacity, as well as elastin and collagen deposition.
These alterations occur in both groups of patients to the same degree.
These findings indicate that cellular and extracellular changes of pulmonary vessels may be originated at an early stage in cigarette smoke-induced respiratory disease, suggesting that tobacco consumption is possibly the direct cause of these changes
Prof. J.A. Barbera | Daily University Science News
Physics of bubbles could explain language patterns
25.07.2017 | University of Portsmouth
Obstructing the ‘inner eye’
07.07.2017 | Friedrich-Schiller-Universität Jena
Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers
Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...
Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.
At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...
3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects
A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...
Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.
For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...
What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.
To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...
26.07.2017 | Event News
21.07.2017 | Event News
19.07.2017 | Event News
26.07.2017 | Physics and Astronomy
26.07.2017 | Life Sciences
26.07.2017 | Earth Sciences