And although 78 per cent said they would tell a family doctor that the prescription they had written would have to be dispensed off-label – outside the terms of the drug’s product license – only 66 per cent felt they had a similar responsibility to inform the child’s parents.
Pharmacists said the most common off-label dispensing of prescribed and over-the-counter medicines involved giving a drug to a child who was younger than the recommended minimum age for the drug or giving them higher than the recommended dose.
Just under 500 community pharmacists, with wide-ranging experience and post-registration education, took part in the research, carried out by the Department of Medicine and Therapeutics at the University of Aberdeen, UK.
“The community pharmacists who responded to the questionnaire appeared to be aware of – and concerned by - the issues surrounding off-label prescribing to children” says co-author Dr James McLay.
“What did concern us was that only 40 per cent of pharmacists said they had dispensed off-label medicines to children in the month before the survey.
“Having reviewed primary care prescribing levels, this 40 per cent figure was lower than expected and leads us to conclude that many pharmacists may not realise that they are dispensing off-label.
“And a third said they didn’t feel they had a responsibility to inform parents of off-label prescribing, possibly because this could suggest criticism of the family doctor who prescribed the drug.”
The researchers also found that most of the 482 randomly-selected pharmacists gained their knowledge of off-label dispensing through work experience rather than education.
“While all licensed medicines used to treat children have been rigorously tested before their general use, not all are specifically licensed for use by children” says Dr McLay.
“Until this situation is rectified, community pharmacists need to be competent and confident in recognising and dealing with drugs that are prescribed and dispensed outside their licensed use.
“Community pharmacists in the UK are responsible for overseeing the supply of prescription and over-the-counter medicine for use by children and ensuring that any off-label drugs are prescribed and dispensed appropriately.
“Give their role, we feel that greater emphasis should be placed on providing them with both undergraduate and postgraduate education in off-label dispensing, together with evidence-based information and training.”
More than 60 per cent of the community pharmacists surveyed said that they had been asked by a member of the public to sell over-the-counter medicines, such as antihistamines, analgesics and steroids, for off-label use in children,
Nearly all the respondents said that they used general drug guidelines or the pack insert to decide whether to dispense the drug, rather than specialist formularies or guidelines on dispensing to children.
“Despite the wide availability of specialised resources, such as Medicine for Children, published by the Royal College of Paediatricians, only one respondent said they used them” says Dr McLay.
“The situation should hopefully improve, as copies of the British National Formulary for Children have been made freely available to community pharmacists since the survey was carried out.”
Annette Whibley | alfa
Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung
High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences