Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

People with early Parkinson's report hallucinations, sleepiness

11.07.2007
People with early Parkinson’s disease report a higher than anticipated development or worsening of hallucinations, sleepiness, and swelling. Researchers have identified factors that make people more likely to develop these problems, according to a study published in the July 10, 2007, issue of Neurology®, the medical journal of the American Academy of Neurology.

“By identifying risk factors, it may help guide treatment decisions, allow for early intervention and possibly reduce disability,” said study author Kevin Biglan, MD, MPH, with University of Rochester School of Medicine in Rochester, NY, and member of the American Academy of Neurology.

For the study, researchers reviewed the results of a four-year clinical trial involving 301 people with an average age of 61 who had early Parkinson’s disease. Half of the group received the drug levodopa; the other half took pramipexole. No one reported having hallucinations at the beginning of the study.

The study found nearly one-fifth developed hallucinations, more than one-third of the participants developed sleepiness, and nearly half developed swelling within four years of starting treatment. Multiple health problems, along with age, gender, initial type of treatment and cognitive status were identified as risk factors.

“In contrast to other studies, we found being male, having multiple health problems and taking pramipexole were independently associated with developing sleepiness,” said Biglan. “This is the first time a patient’s other health problems have been identified as a risk factor for drowsiness.”

The study also found being older, having more multiple health problems and the presence of slight memory problems were associated with an increased risk of hallucinations; type of treatment did not affect the risk.

Being female, having heart disease and pramipexole treatment was associated with an increased risk of swelling.

“Our results suggest that other illnesses are important, yet overlooked risk factors for the development of sleep problems, swelling, and hallucinations in early Parkinson’s disease and should be considered when talking to patients about the risks of treatment,” said Biglan. “When beginning pramipexole, doctors should explain the risks and monitor patients closely for sleep issues and swelling.”

Angela Babb | EurekAlert!
Further information:
http://www.aan.com

More articles from Studies and Analyses:

nachricht WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf

nachricht First form of therapy for childhood dementia CLN2 developed
25.04.2018 | Universitätsklinikum Hamburg-Eppendorf

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Research reveals how order first appears in liquid crystals

23.05.2018 | Life Sciences

Space-like gravity weakens biochemical signals in muscle formation

23.05.2018 | Life Sciences

NIST puts the optical microscope under the microscope to achieve atomic accuracy

23.05.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>