“One of the biggest limitations of current radiofrequency ablation techniques is the inability to effectively treat large tumors” said Paul Laeseke, PhD, lead author of the study. “Current radiofrequency ablation systems can only power one electrode and create relatively small ablation zones,” Dr. Laeseke said. Large tumors are treated by sequentially overlapping the small ablation zones--a technique that is both complicated and time consuming,” he said.
The study consisted of 38 malignant liver tumors in 23 patients who underwent multiple-electrode radiofrequency ablation. Local control was achieved in 37 of 38 tumors, with 34 of these tumors treated during just one session. The total ablation time was reduced by approximately 54% compared to if the patients would have been treated using a single-electrode system, Dr. Laeseke said.
“A reduction in procedure time would make staff and imaging equipment available for other cases,” said Dr. Laeseke. “The treatment success rates in this study are comparable to those reported in the literature for smaller tumors treated with single-electrode radiofrequency,” he said. “In other words, the multiple-electrode system allowed us to effectively treat larger tumors in less time.”
Dr. Laeseke cautioned though that these are short-term results. “While the short-term results are promising and demonstrate that multiple-electrode radiofrequency ablation is safe and effective, longer term follow-up is needed to determine the impact of multiple-electrode radiofrequency ablation on patient survival and tumor recurrence rates,” he said.
The full results of this study appear in the June issue of the American Journal of Roentgenology, published by the American Roentgen Ray Society.
Necoya Lightsey | EurekAlert!
Multi-year study finds 'hotspots' of ammonia over world's major agricultural areas
17.03.2017 | University of Maryland
Diabetes Drug May Improve Bone Fat-induced Defects of Fracture Healing
17.03.2017 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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24.03.2017 | Physics and Astronomy