The study, a world-first carried out by researchers at The University of Nottingham, discovered that children given oral treatment recovered as quickly, suffered less pain, required less oxygen therapy in hospital and were able to go home sooner than those given injections.
Two-and-a-half million children are affected by pneumonia each year in Europe. Until now, most children have been admitted to hospital and treated with injected antibiotics.
The findings suggest that these injections — endured by generations of children — may be unnecessary and could be replaced with oral doses of the medicine in the majority of cases. The study has been published online in the medical journal Thorax.
The research involved 243 children in hospitals throughout the UK. It was led by Terence Stephenson, Professor of Child Health, and Dr Maria Atkinson, both of The University of Nottingham’s Medical School.
The study is the first in the developed world to compare oral treatment versus intravenous (IV) treatment for children with community-acquired pneumonia, who are unwell enough to need admission to hospital.
Professor Stephenson said: “This is good news for children who hate injections; good news for parents whose children will spend less time in hospital; good news for paediatricians who hate sticking needles in children and good news for the NHS, as fewer beds will be occupied and the treatment is cheaper.”
Dame Helena Shovelton, Chief Executive of the British Lung Foundation, said: “Treating childhood pneumonia will be less painful and distressing for parents, for children and for the health professionals caring for them, thanks to this research. We are very proud to have made this breakthrough possible.”
The research project involved 243 children, enrolled over a 21-month period at eight UK hospitals. Half were randomly assigned to receive a week of oral antibiotic treatment and half to receive antibiotics intravenously.
Follow-up over subsequent weeks showed that both types of treatment are effective in tackling the illness — and the former actually had a number of advantages over the latter. Oral antibiotics are also cheaper than those given via the IV route.
The researchers concluded: “We suggest that in countries like the UK, all but the sickest children with community-acquired pneumonia should be treated with oral amoxicillin initially.
“We expect that the majority of children will still require hospital admission but for a shorter period, to ensure oral medication is tolerated, and temperature and respiratory distress are settling. Most importantly children will be spared the pain and distress that injections cause.”
Emma Thorne | alfa
Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT
Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
08.12.2016 | Life Sciences
08.12.2016 | Physics and Astronomy
08.12.2016 | Materials Sciences