Previous studies have suggested a link between HRT use and breast cancer. Ahmedin Jemal and colleagues at the American Cancer Society conducted statistical analysis to examine patterns in invasive and in situ breast cancer incidence in relation to age, tumour size at diagnosis and disease stage. Regular mammography screening starts at 40 and HRT is most common in women aged 50 or older, so the study focussed on women age 40 and above.
The research team examined trends in breast cancer incidence in the National Cancer Institute’s Surveillance Epidemiology and End Results database from 1975 to 2003. The database includes women from 5 US States (Connecticut, Hawaii, Iowa, New Mexico, and Utah) and 5 metropolitan cities (Atlanta, Detroit, San-Francisco, and Seattle). Almost 400,000 invasive and 60,000 in situ cases of breast cancer were diagnosed in that time. Breast cancer incidence rates increased by almost 40% between 1980 and 1998, and then showed a downward trend with a dramatic decrease from 2002 to 2003. The greatest decline was in women who had small tumours, early stage disease, estrogen/progestin positive tumours, and who were aged 55 or older.
Jemal et al concluded that the speed of decrease in breast cancer incidence, following the dramatic reduction in HRT use after the Women’s Health initiative publication in 2002, likely reflects the early consequences of reductions in HRT use, while the downturn in incidence rates across multiple age groups beginning 1998/1999 reflects the saturation of mammography.
The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft
Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung
Controlling electronic current is essential to modern electronics, as data and signals are transferred by streams of electrons which are controlled at high speed. Demands on transmission speeds are also increasing as technology develops. Scientists from the Chair of Laser Physics and the Chair of Applied Physics at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have succeeded in switching on a current with a desired direction in graphene using a single laser pulse within a femtosecond ¬¬ – a femtosecond corresponds to the millionth part of a billionth of a second. This is more than a thousand times faster compared to the most efficient transistors today.
Graphene is up to the job
At the productronica trade fair in Munich this November, the Fraunhofer Institute for Laser Technology ILT will be presenting Laser-Based Tape-Automated Bonding, LaserTAB for short. The experts from Aachen will be demonstrating how new battery cells and power electronics can be micro-welded more efficiently and precisely than ever before thanks to new optics and robot support.
Fraunhofer ILT from Aachen relies on a clever combination of robotics and a laser scanner with new optics as well as process monitoring, which it has developed...
Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.
A warming planet
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
26.09.2017 | Life Sciences
26.09.2017 | Physics and Astronomy
26.09.2017 | Information Technology