Previous studies have suggested a link between HRT use and breast cancer. Ahmedin Jemal and colleagues at the American Cancer Society conducted statistical analysis to examine patterns in invasive and in situ breast cancer incidence in relation to age, tumour size at diagnosis and disease stage. Regular mammography screening starts at 40 and HRT is most common in women aged 50 or older, so the study focussed on women age 40 and above.
The research team examined trends in breast cancer incidence in the National Cancer Institute’s Surveillance Epidemiology and End Results database from 1975 to 2003. The database includes women from 5 US States (Connecticut, Hawaii, Iowa, New Mexico, and Utah) and 5 metropolitan cities (Atlanta, Detroit, San-Francisco, and Seattle). Almost 400,000 invasive and 60,000 in situ cases of breast cancer were diagnosed in that time. Breast cancer incidence rates increased by almost 40% between 1980 and 1998, and then showed a downward trend with a dramatic decrease from 2002 to 2003. The greatest decline was in women who had small tumours, early stage disease, estrogen/progestin positive tumours, and who were aged 55 or older.
Jemal et al concluded that the speed of decrease in breast cancer incidence, following the dramatic reduction in HRT use after the Women’s Health initiative publication in 2002, likely reflects the early consequences of reductions in HRT use, while the downturn in incidence rates across multiple age groups beginning 1998/1999 reflects the saturation of mammography.
WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf
First form of therapy for childhood dementia CLN2 developed
25.04.2018 | Universitätsklinikum Hamburg-Eppendorf
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.
The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...
Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.
Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...
A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.
Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...
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