Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

USC-led study suggests exercise reduces risk of developing invasive breast cancer

28.02.2007
Women exercising for five or more hours per week experienced greater decrease in risk of breast cancer compared to less active women

Significant findings have emerged from the California Teachers Study (CTS) that suggest long-term recreational physical activity plays a protective role against invasive and in situ breast cancer.

"Previous studies have linked physical activity with a reduction in breast cancer, but few studies have examined risk separately for in situ and invasive breast cancers or have characterized risk by hormone receptor status," said Leslie Bernstein, professor of preventive medicine at the Keck School of Medicine of USC and primary investigator of the CTS. "This study is unique because it provides the first prospective study data documenting that a woman's long-term exercise habits are important in determining her future breast cancer risk."

In a study to be published in the February 26 issue of the Archives of Internal Medicine, researchers analyzed data collected from a cohort of 110,599 women who were current or former California teachers and public school professionals with no prior history of breast cancer, and who were between the ages of 22 and 79 years at the start of the study. The study was initiated in 1995 with detailed collection of information on women's exercise histories and current exercise habits.

The study focused on the impact of strenuous activities, as well as moderate activities, collecting information on the amount each woman exercised per week from high school through age 54 years (or the woman's current age if she was younger than 54). Women were followed through the end of 2002 using information from California's statewide comprehensive cancer registry to identify which women developed breast cancer. During the 6.5 year follow-up period, 2,649 women were diagnosed with invasive breast cancer and 593 were diagnosed with in situ breast cancer, meaning the cancer was confined to the ducts or lobules of the breast.

Invasive breast cancer risk was reduced among women participating in strenuous activity, such as swimming, jogging, or participating in aerobics activities for more than five hours per week annually, when compared to the least active women. Similar results were seen for in situ breast cancer risk.

One unique finding in this study is that the benefit of long-term strenuous activity was only seen among invasive breast cancer patients with ER-negative tumors. Previous studies have suggested little to no difference in the effect of physical activity by hormone receptor status.

"This finding was somewhat unexpected; however, if it is repeated in future studies of physical activity and breast cancer risk, in offers a promising complement to our current approaches to preventing breast cancer, namely the use of drugs that block estrogens, like tamoxifen or raloxifene. These drugs seem to be effective in reducing risk of ER-positive cancers, but do not impact the occurrence of ER-negative cancers," says Bernstein.

"This study confirms that breast cancer risk is influenced by consistent participation in strenuous forms of exercise activity. However, it may require substantial commitment of time to achieve this lower risk," concludes Bernstein. "This study showed that risk was lower for women who exercised at least 5 hours per week and our prior studies of other groups of women have suggested a minimum of 3-4 hours per week."

Jennifer Chan | EurekAlert!
Further information:
http://www.usc.edu

More articles from Studies and Analyses:

nachricht Antarctic Ice Sheet mass loss has increased
14.06.2018 | Technische Universität Dresden

nachricht WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: AchemAsia 2019 will take place in Shanghai

Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.

Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...

Im Focus: First real-time test of Li-Fi utilization for the industrial Internet of Things

The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.

Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.

Im Focus: Sharp images with flexible fibers

An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.

Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...

Im Focus: Photoexcited graphene puzzle solved

A boost for graphene-based light detectors

Light detection and control lies at the heart of many modern device applications, such as smartphone cameras. Using graphene as a light-sensitive material for...

Im Focus: Water is not the same as water

Water molecules exist in two different forms with almost identical physical properties. For the first time, researchers have succeeded in separating the two forms to show that they can exhibit different chemical reactivities. These results were reported by researchers from the University of Basel and their colleagues in Hamburg in the scientific journal Nature Communications.

From a chemical perspective, water is a molecule in which a single oxygen atom is linked to two hydrogen atoms. It is less well known that water exists in two...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Munich conference on asteroid detection, tracking and defense

13.06.2018 | Event News

2nd International Baltic Earth Conference in Denmark: “The Baltic Sea region in Transition”

08.06.2018 | Event News

ISEKI_Food 2018: Conference with Holistic View of Food Production

05.06.2018 | Event News

 
Latest News

Novel method for investigating pore geometry in rocks

18.06.2018 | Earth Sciences

Diamond watch components

18.06.2018 | Process Engineering

New type of photosynthesis discovered

18.06.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>