A new study to be published in an upcoming edition of the journal of Diabetes Research and Clinical Practice reveals that French maritime pine tree extract known as Pycnogenol® (pic-noj-en-all) delays the uptake of glucose from a meal 190 times more than prescription medications, preventing the typical high-glucose peak in the blood stream after a meal. The study revealed the pine bark is more potent for suppressing carbohydrate absorption in diabetes than synthetic prescription alpha-glucosidase inhibitors such as Precose®.
"Diabetes mellitus type II is a serious disease with rising prevalence," said Dr. Petra Högger, a lead researcher of this study. "This study is crucial for those suffering with the disease because it affirms that Pycnogenol® is more effective than prescription medication Precose® and supports the abundance of other research done on Pycnogenol® and diabetes."
The study was conducted at the University of Wurzburg Germany. Dr. Högger investigated the interaction of Pycnogenol® with the enzyme alpha-glucosidase, which breaks down carbohydrates in a meal. Results revealed Pycnogenol® is 190 times more potent for inhibition of alpha-glucosidase than the synthetic inhibitor acarbose, a common prescription medication for treatment of type II diabetes (sold in Europe under the name Glucobay® and the United States under the name Precose™).
Pycnogenol® was shown to inhibit the intestinal enzymes (alpha-glucosidase) involved in the digestion of complex carbohydrates such as starch and normal table sugar. The alpha-glucosidase breaks down carbohydrates into glucose molecules which are then absorbed into the blood stream.
"The high concentration of procyanidins (flavonoids) found in Pycnogenol® is responsible for demonstrating these excellent results," said Högger. According to Högger, the large procyanidin molecules were found to be particularly active for inhibiting the activity of alpha-glucosidase, thus demonstrating such notable results. "The carbohydrates enter the blood stream steadily over prolonged periods of time, which make meals last longer and prolong satiety."
In two separate studies conducted in 2004, Pycnogenol® was found to significantly lower blood sugar levels in type II diabetes patients. A study published in the March 2004 edition of Diabetes Care revealed that patients who supplemented with Pycnogenol® experienced lower blood sugar after meals and lower fasting blood sugar. Another study published in the October edition of Life Sciences revealed a significantly further lowered blood glucose level in patients who supplemented with Pycnogenol® while continuing their anti-diabetic medication with acarbose and metformin.
This study opens new avenues for product development of Pycnogenol® in the field of diabetes, metabolic syndrome and obesity. "With seven percent of Americans diagnosed with diabetes, more than one in five people afflicted with metabolic syndrome, and 60 million U.S. adults considered obese, finding natural and safe options for managing these conditions and improving quality of life is a priority," said Högger.
Pycnogenol® is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins, bioflavonoids and organic acids, which offer extensive natural health benefits. The extract has been widely studied for the past 35 years and has more than 220 published studies and review articles ensuring safety and efficacy as an ingredient. Today, Pycnogenol® is available in more than 600 dietary supplements, multi-vitamins and health products worldwide.
Melanie Nimrodi | EurekAlert!
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
28.04.2017 | Event News
20.04.2017 | Event News
18.04.2017 | Event News
28.04.2017 | Medical Engineering
28.04.2017 | Earth Sciences
28.04.2017 | Life Sciences