Patients with obstructive sleep apnea (OSA) may improve their memory by using continuous positive airway pressure (CPAP). A new study published in the December issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), shows that the majority of patients with OSA, who were memory-impaired prior to treatment, demonstrated normal memory performance after 3 months of optimal CPAP use.
The study also showed that memory improvement varied based on CPAP adherence. Patients who used CPAP for at least 6 hours a night were nearly eight times as likely to demonstrate normal memory abilities compared with patients who used CPAP for 2 or fewer hours a night.
"Patients with OSA often complain of daily forgetfulness, eg, losing their keys, forgetting phone numbers, or forgetting to complete daily tasks," said senior study author Mark S. Aloia, PhD, National Jewish Medical and Research Center in Denver, CO, who conducted his research while at Brown University Medical School, Providence, RI. "Where memory is concerned, we may have the ability to reverse some of the impairments by providing effective and consistent use of CPAP treatment."
Dr. Aloia and colleagues examined the degree to which varying levels of CPAP adherence improved memory in 58 memory-impaired patients with clinically diagnosed OSA. All patients underwent cognitive evaluation involving verbal memory testing prior to initiation of CPAP and at a 3-month follow-up visit. Patients were prescribed CPAP machines, and adherence was covertly monitored using internal microprocessors within each device. After treatment, patients were divided into three groups based on their 3-month CPAP adherence: (1) poor users (n=14), patients who averaged fewer than 2 hours/night of CPAP use; (2) moderate users (n=25), patients who averaged 2 to 6 hours/night of CPAP use; and (3) optimal users (n=19), patients who averaged more than 6 hours/night of CPAP use.
At baseline, all patients were found equally impaired in verbal memory, with the average verbal memory score being approximately 2 SD below the mean for all participants. Following 3 months of CPAP treatment, 21 percent of poor users, 44 percent of moderate users, and 68 percent of optimal users demonstrated normal memory performance. Compared with poor users, optimal users of CPAP were nearly eight times as likely to demonstrate normal memory abilities. Overall, the average verbal memory score for all patients improved approximately 1 SD.
"Moderate use of CPAP may help, but it might not allow patients to reach their full potential recovery where memory is concerned, especially if memory is impaired at baseline," said Dr. Aloia. "For patients with OSA, the more regularly and consistently they use CPAP, the better off they will be." Dr. Aloia believes that getting patients to use CPAP at least 6 hours a night could be a challenge for physicians. "Our findings also suggest that this optimal level of CPAP adherence is uncommon following 3 months of treatment," said Dr. Aloia. "We need to find ways of encouraging patients to use their treatment all night, every night in order to optimize treatment response."
"CPAP has proven to be an effective treatment for patients with OSA, yet adherence to treatment remains poor," said Mark J. Rosen, MD, FCCP, President of the American College of Chest Physicians. "Physicians should educate their patients with OSA about the importance of using CPAP consistently and discuss ways to overcome obstacles to adherence."
Jennifer Stawarz | EurekAlert!
Rutgers-led innovation could spur faster, cheaper, nano-based manufacturing
14.02.2018 | Rutgers University
New study from the University of Halle: How climate change alters plant growth
12.01.2018 | Martin-Luther-Universität Halle-Wittenberg
Satellites in near-Earth orbit are at risk due to the steady increase in space debris. But their mission in the areas of telecommunications, navigation or weather forecasts is essential for society. Fraunhofer FHR therefore develops radar-based systems which allow the detection, tracking and cataloging of even the smallest particles of debris. Satellite operators who have access to our data are in a better position to plan evasive maneuvers and prevent destructive collisions. From April, 25-29 2018, Fraunhofer FHR and its partners will exhibit the complementary radar systems TIRA and GESTRA as well as the latest radar techniques for space observation across three stands at the ILA Berlin.
The "traffic situation" in space is very tense: the Earth is currently being orbited not only by countless satellites but also by a large volume of space...
An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.
The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...
In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.
Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...
Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.
They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...
A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...
23.03.2018 | Event News
19.03.2018 | Event News
16.03.2018 | Event News
23.03.2018 | Materials Sciences
23.03.2018 | Agricultural and Forestry Science
23.03.2018 | Physics and Astronomy