The team reports in the December 5 Annals of Internal Medicine that routine HIV screening is cost-effective, even in communities where as few as two in 1,000 people have undiagnosed HIV infection.
The study provides strong support for U.S. Centers for Disease Control and Prevention guidelines issued in September 2006 that recommend routine HIV screening of all persons age 13 to 64 in all health care settings. The guidelines were based in part on findings of the study team led by A. David Paltiel, professor in the Department of Epidemiology and Public Health at the Yale School of Medicine, and the Yale School of Management.
"HIV screening delivers better value than many other diagnostic tests and treatments that physicians use routinely in daily practice, including screening for breast cancer, colorectal cancer, diabetes and hypertension," said Paltiel, who cites the roughly 300,000 Americans who do not know they are infected with HIV as the reason to make HIV screening as routine as measuring cholesterol. "Early identification of HIV saves lives."
Paltiel and his colleagues developed a mathematical model to simulate the events that occur in an HIV-infected person, including detection, treatment, medical expenses, transmitting the disease to others, and death. The model calculated the additional costs due to screening and the additional survival attributable to earlier detection. It also calculated how much life was shortened by HIV infection. The model then estimated the cost per extra year of life gained (cost-effectiveness) from HIV screening.
"The HIV epidemic is no longer confined to a handful of identifiable risk groups, yet current approaches to HIV testing still focus on the old target populations," said study co-author Kenneth Freedberg, M.D., director of HIV Outcomes Research at the Harvard Medical School, who is also affiliated with the Partners AIDS Research Center at Massachusetts General Hospital.
The authors caution that the study’s findings hinge on the assumption that persons identified with HIV will be linked to state-of-the art, life-saving care. "There is no point searching for needles in haystacks if you merely plan to throw them back in," said Paltiel. "The CDC’s commitment to expanded HIV screening must be accompanied by an equally bold financial commitment from the state and federal agencies that provide and pay for HIV care."
Karen N. Peart | EurekAlert!
WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf
First form of therapy for childhood dementia CLN2 developed
25.04.2018 | Universitätsklinikum Hamburg-Eppendorf
A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...
At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
02.05.2018 | Event News
13.04.2018 | Event News
12.04.2018 | Event News
24.05.2018 | Ecology, The Environment and Conservation
24.05.2018 | Medical Engineering
24.05.2018 | Physics and Astronomy