Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Pediatric heart condition's origin, prevalence mirror adults

19.10.2006
The mystery behind a commonly untreatable and undetected heart muscle disease in children is partially revealed for the first time in today's edition of the scientific journal JAMA.

In a multi-center, international study, researchers at Baylor College of Medicine (BCM) and Texas Children's Hospital (TCH) in Houston showed the underlying causes, frequencies, and outcomes of dilated cardiomyopathy (DCM), which often leads to heart failure, paralleling those in adults with DCM. The study also found DCM to be more common among boys of all races and in blacks compared to whites.

"Children with dilated cardiomyopathy are at the same level of risk as adults of having sudden cardiac death and needing transplants," said senior author Dr. Jeffrey Towbin, professor of pediatrics at BCM and chief of pediatric cardiology at TCH. "It is a major cause of death in children just like it is in adults."

Funded by the National Heart, Lung, and Blood Institute, one of the National Institutes of Health, the study identified the causes in 35 percent of the 1,400 cases of pediatric DCM studied, the most common one being myocarditis (inflammation of the heart). The origins of the roughly two-thirds of cases studied were unknown. Infants (less than one year old) were almost ten times more likely to develop DCM than any other pediatric age group (up to 18 years old) studied.

Survival rates for children with DCM were also found to be approximately the same as in adults with the condition. In both groups, around 70 percent live beyond the first year of the disorder's onset, and only 50 percent survive past five years.

DCM, the most common form of cardiomyopathy at any age, occurs when the left ventricle, the heart's major pumping chamber, becomes enlarged and cannot pump effectively, usually resulting in heart arrhythmia, heart failure, and the possible need for a heart transplant. Other forms of cardiomyopathy are characterized by the heart's inability to relax appropriately between pumps, and their outcomes are commonly sudden, unexpected cardiac death.

Roughly one-third of all cases of DCM are genetic in origin. Towbin recommends that people with a family history of DCM be tested for the disorder.

"Even though we can't always determine what the cause is, we know if it's inherited," Towbin said. "With an early diagnosis, we can begin therapy and assess whether transplantation is necessary."

Although these findings represent a major stride toward better understanding and treating DCM, Towbin says much work remains.

"Despite advances in diagnosis and treatment, we are still having significant problems with outcomes in these children just like we are in adults," said Towbin. "There needs to be more support for research in this area."

Ross Tomlin | EurekAlert!
Further information:
http://www.bcm.edu

More articles from Studies and Analyses:

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

nachricht Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

Im Focus: Using graphene to create quantum bits

In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.

In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

Physicists discover mechanism behind granular capillary effect

24.05.2017 | Physics and Astronomy

Measured for the first time: Direction of light waves changed by quantum effect

24.05.2017 | Physics and Astronomy

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>