Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Independent evaluation finds GAVI funding to poor countries can boost childhood vaccine coverage

19.09.2006
But countries with initial coverage greater than 65% showed no effect

The Global Alliance for Vaccines and Immunization (GAVI) was created in 1999 with the goal of enabling even the poorest countries to provide vaccines to all children. A study by researchers associated with the Harvard Initiative for Global Health set out to measure the extent to which GAVI funding had succeeded in raising the percentage of children who received the combined diphtheria, tetanus and pertussis vaccine (DTP3) and whether the cost had been close to GAVI's original estimates of $20 per additional child immunized.

Their analysis appears in advance online in the September 21, 2006 issue of the Lancet, www.thelancet.com.

GAVI is a public-private global health partnership that was created when vaccine coverage in many countries was dropping. Countries with a gross national income of less than US$1000 per capita per year and with coverage under 80% were eligible to receive financial support from GAVI to develop immunization services, including personnel, infrastructure and supplies, as part of their national health system. Decisions on how resources are spent are left to the individual countries, but continued authorization of funding is tied to meeting yearly immunization coverage targets set by the countries.

Research Associate Chunling Lu and colleagues from the Harvard School of Public Health (HSPH) analyzed the relationship between DTP3 coverage for GAVI recipient countries from 1995 to 2004 and immunization services spending (ISS) per surviving child in 53 countries. The analysis revealed that in countries with DTP3 coverage of 65% or less at the start of the program, ISS spending had a significant positive effect on DTP3 coverage, raising coverage from under 50% in many countries to close to 65%.

However, in countries with initial DTP3 coverage of more than 65%, GAVI spending did not translate into increased immunization coverage.

The estimated cost per additional child immunized was less than $14. But if non-ISS expenditures are included, such as for new and underused vaccine and safe injection equipment, the cost per child approaches $20, close to GAVI's original estimates.

Between 2000 and 2005, total GAVI disbursements were $760.5 million, of which $124-125 million (16%) were for immunization services spending.

Based on their analysis, the researchers recommend that GAVI consider redistributing its resources to countries with the lowest immunization coverage.

"Assessment of the effect of GAVI is important not only because of the alliance's mission and the resources devoted to this effort," write the researchers, "but also because the project represents an important innovation in global health. Together with Stop TB and Roll Back Malaria, GAVI was one of the first major global health initiatives designed to create new public-private partnerships to tackle major health problems."

Unlike these other global health initiatives, however, for which there is no reliable indicator of effect on health, GAVI afforded an opportunity for concrete measure of public health improvement.

"This is the first time that there is hard evidence that one of the major global health programs is having a real impact; the world desperately needs similar analyses for AIDS, tuberculosis, malaria and other initiatives," said senior author Christopher J. Murray, Richard Saltonstall Professor of Population Policy at HSPH and director of the Harvard Initiative for Global Health.

Said Lu: "Our research shows conclusively that GAVI, as an experiment to provide financial help to countries with poor performance in DTP3 coverage, is effective in bringing vaccine protection to the world's most disadvantaged children."

Todd Datz | EurekAlert!
Further information:
http://www.hsph.harvard.edu

More articles from Studies and Analyses:

nachricht A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg

nachricht Urbanization to convert 300,000 km2 of prime croplands
27.12.2016 | Mercator Research Institute on Global Commons and Climate Change (MCC) gGmbH

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

Im Focus: Bacterial Pac Man molecule snaps at sugar

Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.

The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

Water - as the underlying driver of the Earth’s carbon cycle

17.01.2017 | Earth Sciences

Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

17.01.2017 | Materials Sciences

Smart homes will “LISTEN” to your voice

17.01.2017 | Architecture and Construction

VideoLinks
B2B-VideoLinks
More VideoLinks >>>