Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Adverse effects and costs of chemotherapy greater than previously thought

17.08.2006
Researchers at Dana-Farber Cancer Institute and Harvard Medical School have found that breast cancer patients 63 years of age or younger may experience more chemotherapy-related serious adverse effects than reported in clinical trials, according to a new study in the August 16 issue of the Journal of the National Cancer Institute.

Led by Michael J. Hassett, MD, MPH, of Dana-Farber, researchers studied a database of medical claims made by women with newly diagnosed breast cancer who had employer-provided health insurance between January 1998 and December 2002.

"This is the first study, to our knowledge, of chemotherapy-related serious adverse effects in a population-based sample of younger women with breast cancer," said Hassett, who is also an instructor in medicine at Harvard Medical School. "We found that eight chemotherapy-related serious adverse effects may be more common than reported in large clinical trials, and, therefore, these adverse effects may be responsible for more patient suffering and higher health care expenditures than currently predicted."

Doctors often prescribe chemotherapy to eliminate residual cancer cells in women who have undergone surgery for breast cancer. Women who received chemotherapy were more likely to be hospitalized or visit emergency rooms for problems that are typically related to chemotherapy, including fever or infection, low white blood cell or platelet count, nausea, diarrhea, malnutrition, or dehydration.

Researchers studied 7,052 women from a database of claims made to health plans that contract with large employers in the U.S. The group was equally divided into two cohorts of 3,526: those who received chemotherapy within 12 months of their first breast cancer diagnosis, and those who did not.

In addition to more incidents of chemotherapy-related adverse effects, women undergoing chemotherapy for breast cancer also experienced increased healthcare costs: $1,271 more per year for hospitalizations and emergency room visits and $17,617 more per year for ambulatory care than women who did not receive chemotherapy.

Additional contributors of the report are from Dana-Farber and the Harvard School of Public Health.

Teresa Herbert | EurekAlert!
Further information:
http://www.dana-farber.org

More articles from Studies and Analyses:

nachricht Drone vs. truck deliveries: Which create less carbon pollution?
31.05.2017 | University of Washington

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Study shines light on brain cells that coordinate movement

26.06.2017 | Life Sciences

Smooth propagation of spin waves using gold

26.06.2017 | Physics and Astronomy

Switchable DNA mini-machines store information

26.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>