Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study shows new drug helps elderly with insomnia

26.07.2006
The drug eszopiclone, marketed as Lunesta, significantly improved sleep in elderly people with chronic insomnia, according to a report by W. Vaughn McCall, M.D., M.S., and six colleagues.

"Eszopiclone was well tolerated and significantly improved sleep onset, sleep efficiency, total sleep time and sleep quality over the study period," said McCall, director of the sleep laboratory at Wake Forest University Baptist Medical Center and professor and chairman of the Department of Psychiatry and Behavioral Medicine, in the study published in Current Medical Research and Opinion.

He said eszopiclone significantly reduced wakefulness after sleep had begun, wake time during the sleep period and daytime napping.

McCall said daytime napping was more common in elderly patients with insomnia than in good sleepers and that napping increases with age. "The finding of less daytime napping associated with eszopiclone treatment in the present study could be interpreted as evidence of improvement in some aspects of daytime function in these elderly insomniacs."

The study compared eszopiclone with an inert placebo in patients 64 to 86 years old over a two-week period and used both measurements made in sleep laboratories and patients' own reports of their sleep activity during the study.

The 136 patients in the eszopiclone group reported greater quality of sleep and greater depth of sleep than the 128 patients in the control group, he said. "Upon awakening, patients treated with eszopiclone reported less morning sleepiness compared with placebo."

Since patients were in the study for only two weeks, McCall said longer-term studies are needed to determine the safety of longer treatment. The study – conducted in 49 sleep laboratories -- was the largest sleep-lab-based trial of nightly doses of a sleeping pill in elderly patients with insomnia, he said.

"Chronic insomnia is an under-recognized, under-diagnosed and under-treated disorder that is not only more prevalent in the elderly than the general population, but also potentially serious, as it can be associated with increased risk for injurious falls and impairment of cognitive function, which can be misdiagnosed as dementia," McCall and his colleagues said. "In patients with dementia, insomnia is also the most frequently cited reason for nursing home placement."

Robert Conn | EurekAlert!
Further information:
http://www.wfubmc.edu

More articles from Studies and Analyses:

nachricht Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT

nachricht Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

Im Focus: Fraunhofer ISE Develops Highly Compact, High Frequency DC/DC Converter for Aviation

The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.

Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

UTSA study describes new minimally invasive device to treat cancer and other illnesses

02.12.2016 | Medical Engineering

Plasma-zapping process could yield trans fat-free soybean oil product

02.12.2016 | Agricultural and Forestry Science

What do Netflix, Google and planetary systems have in common?

02.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>