Prof. Maksymowych, Division of Rheumatology, University of Alberta, Edmonton, Canada, and his radiologist colleagues recognized the importance of image-guided IA steroid placement for accurate treatment and the significant effects this might have on the clinical responses in an earlier trial showing that the treatment was not effective. Precision image-guided injections can be very helpful and at times are essential to help localize the structural origin of a patient’s pain, especially in places where it might be difficult to detect the pain source, such as in the hip and the spine.
OA is the most common type of arthritis affects approximately 2.95 women per 1000 population and approximately 1.71 men per 1000 population.2 The typical symptoms of hip OA are stiffness, as well as pain, which is usually felt in the groin, but may radiate to the knee, buttock, or inner thigh, and is mainly felt on weight-bearing and aggravated by movement. Over time, the patient might get increased stiffness and might find it difficult to reach down to tie shoe laces, or put on socks and shoes. The functional ability may also progress to difficulties in rising from a chair, using stairs, walking and dressing.
The 52 patients enrolled in the trial, received fluoroscopically guided IA injection and were randomly allocated placebo (2 ml of normal saline) or 40 mg of the treatment (triamcinolone hexacetonide). Assessments were performed at baseline, one and two months post-injection. The study found that the patients given steroids improved significantly compared to placebo in all primary and secondary endpoints; pain, stiffness, physical function and global assessment, after 2 months.
“This is very encouraging data, which I believe will have a great response in the medical community. Because there is no cure, the therapeutic goal of treatment for osteoarthritis is to minimize the effects of the disease and its consequences over time. The study shows that the treatment with steroids offers many patients with late stage OA some hope of pain relief when conservative therapy has failed”, said Prof. Maksymowych.
Mia Gannedahl | alfa
Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
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Scientists reveal source of human heartbeat in 3-D
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Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
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A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
Researchers from the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science, the Italian Space Agency (ASI), and the Instituto Geofisico--Escuela Politecnica Nacional (IGEPN) of Ecuador, showed an increasing volcanic danger on Cotopaxi in Ecuador using a powerful technique known as Interferometric Synthetic Aperture Radar (InSAR).
The Andes region in which Cotopaxi volcano is located is known to contain some of the world's most serious volcanic hazard. A mid- to large-size eruption has...
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