Scientists have successfully conducted the first clinical trial giving xenon gas to patients undergoing coronary artery bypass grafting in order to safeguard against postoperative brain damage that can occur following this procedure.
Research published in Anesthesiology shows how the team safely gave xenon to 12 patients undergoing coronary artery bypass grafting while on cardiopulmonary artery bypass, a step which could eventually lead to new treatments for people suffering from illnesses that damage nerve cells, such as strokes, and brain and spinal cord injuries.
Earlier preclinical work by the team showed that xenon was effective as a neuroprotectant, stopping processes present during strokes or brain and spinal cord injuries that would damage nerve cells. They found that xenon was capable of blocking the effects of a particular type of glutamate receptor, the same receptor implicated in the pathway that leads to nerve cell death.
Tony Stephenson | alfa
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