There is little doubt that alcohol-related disorders in humans are genetically based. The influence of environmental factors, however, remains unclear. Given that studies of humans are complicated by a multitude of cultural and day-to-day-living factors, researchers in the March issue of Alcoholism: Clinical & Experimental Research use rhesus monkeys to examine genetic and environmental influences on alcohol consumption. Results indicate that, just as with humans, both genetic and environmental factors contribute to variation in alcohol consumption among the non-human primates.
"Rhesus macaques provide a good model for many human diseases due in part to their phylogenetic closeness," said Joseph G. Lorenz, research associate at the Coriell Institute for Medical Research and corresponding author for the study. "Also, like humans, they are highly social, which is important for diseases like alcoholism where there are social factors affecting alcohol consumption. And, finally, because we can control their social environment and precisely measure their exposure to alcohol, whereas human studies often rely on self-reported consumption patterns."
Researchers examined data drawn from an ongoing longitudinal study of genetic and environmental factors affecting the neurobiology, behavior and alcohol consumption among rhesus macaques. For this particular analysis, study authors investigated factors that may have contributed to variation in alcohol consumption among 156 monkeys during a period of 10 years when they were considered adolescents (between 2 and 4 years of age). All belonged to a single extended pedigree, and received identical early rearing backgrounds and subsequent treatments. Alcohol consumption was measured during unfettered and simultaneous access to both aspartame-sweetened (8.4% v/v) alcohol-water solution as well as water for one hour each day during early afternoon for a period of five to seven weeks.
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
Two researchers at Heidelberg University have developed a model system that enables a better understanding of the processes in a quantum-physical experiment...
Glaciers might seem rather inhospitable environments. However, they are home to a diverse and vibrant microbial community. It’s becoming increasingly clear that they play a bigger role in the carbon cycle than previously thought.
A new study, now published in the journal Nature Geoscience, shows how microbial communities in melting glaciers contribute to the Earth’s carbon cycle, a...
20.04.2017 | Event News
18.04.2017 | Event News
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21.04.2017 | Physics and Astronomy
21.04.2017 | Health and Medicine
21.04.2017 | Physics and Astronomy