Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Newer antibiotic more effective at treating elders’ pneumonia

25.01.2006


A newer antibiotic medication proved more effective at knocking out community-acquired pneumonia (CAP) in patients 65 and older than the antibiotic that has been the front-line CAP treatment the last decade, according to a national study coordinated at The University of Texas Health Science Center at San Antonio.



CAP is the fifth-leading cause of death in the elderly, is diagnosed in 5.6 million adults annually in the U.S., and is 60 percent more likely to occur in the elderly than in the general population. The Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE) study, led by Antonio Anzueto, M.D., professor of medicine at the Health Science Center, is reported in the current issue of Clinical Infectious Diseases.

"The CAPRIE study is very unique in that it was conducted only in patients 65 and older, such as the median age was 78," Dr. Anzueto said. "Community-acquired pneumonia is a common infectious disease process in the elderly. Pneumonia has been identified as the leading infectious disease associated with the higher mortality (death) in this age group. This is also the first time the two leading antibiotics for CAP have been compared in a well-controlled clinical trial."


Treated with the newer medication, moxifloxacin HCI, 97.9 percent of hospitalized patients recovered within three to five days of therapy onset, compared to 90 percent of patients treated with the standard medication, levofloxacin. Study findings were in 281 patients at 47 centers.

"At the end of the day, another important question was safety," Dr. Anzueto said. "This study involved very sophisticated assessment of cardiac safety. We found both treatments to be safe." San Antonio patients were treated at the South Texas Veterans Health Care System.

Moxifloxacin HCI’s greater efficacy earlier in hospital stays should lead to less occurrence of incapacitating long-term effects, Dr. Anzueto said.

Moxifloxacin HCI and levofloxacin are in a group of antibiotics known as fluoroquinolones.

Will Sansom | EurekAlert!
Further information:
http://www.uthscsa.edu

More articles from Studies and Analyses:

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

nachricht Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

NASA Protects its super heroes from space weather

17.08.2017 | Physics and Astronomy

Spray-on electric rainbows: Making safer electrochromic inks

17.08.2017 | Materials Sciences

Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

17.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>