Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Newer antibiotic more effective at treating elders’ pneumonia

25.01.2006


A newer antibiotic medication proved more effective at knocking out community-acquired pneumonia (CAP) in patients 65 and older than the antibiotic that has been the front-line CAP treatment the last decade, according to a national study coordinated at The University of Texas Health Science Center at San Antonio.



CAP is the fifth-leading cause of death in the elderly, is diagnosed in 5.6 million adults annually in the U.S., and is 60 percent more likely to occur in the elderly than in the general population. The Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE) study, led by Antonio Anzueto, M.D., professor of medicine at the Health Science Center, is reported in the current issue of Clinical Infectious Diseases.

"The CAPRIE study is very unique in that it was conducted only in patients 65 and older, such as the median age was 78," Dr. Anzueto said. "Community-acquired pneumonia is a common infectious disease process in the elderly. Pneumonia has been identified as the leading infectious disease associated with the higher mortality (death) in this age group. This is also the first time the two leading antibiotics for CAP have been compared in a well-controlled clinical trial."


Treated with the newer medication, moxifloxacin HCI, 97.9 percent of hospitalized patients recovered within three to five days of therapy onset, compared to 90 percent of patients treated with the standard medication, levofloxacin. Study findings were in 281 patients at 47 centers.

"At the end of the day, another important question was safety," Dr. Anzueto said. "This study involved very sophisticated assessment of cardiac safety. We found both treatments to be safe." San Antonio patients were treated at the South Texas Veterans Health Care System.

Moxifloxacin HCI’s greater efficacy earlier in hospital stays should lead to less occurrence of incapacitating long-term effects, Dr. Anzueto said.

Moxifloxacin HCI and levofloxacin are in a group of antibiotics known as fluoroquinolones.

Will Sansom | EurekAlert!
Further information:
http://www.uthscsa.edu

More articles from Studies and Analyses:

nachricht Rutgers-led innovation could spur faster, cheaper, nano-based manufacturing
14.02.2018 | Rutgers University

nachricht New study from the University of Halle: How climate change alters plant growth
12.01.2018 | Martin-Luther-Universität Halle-Wittenberg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Contacting the molecular world through graphene nanoribbons

19.02.2018 | Materials Sciences

When Proteins Shake Hands

19.02.2018 | Materials Sciences

Cells communicate in a dynamic code

19.02.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>