Scientists have identified 570 genes that act abnormally during the development of Parkinson’s Disease, a finding which could help doctors predict the likelihood of it developing, and provide targets for new treatments.
The research published in Neurogenetics, by the team from Imperial College London and the University of Liege, Belgium, uses microarrays to analyse brains from Parkinson’s patients. Microarrays are laboratory chips able to pick out which genes are active when different processes are occurring in the brain. When they analysed brains from people with Parkinson’s, they found that out of all 25,000 human genes, regulation of 570 was highly abnormal in Parkinson’s brains compared with non-diseased brains. This is the first study on Parkinsons disease where all human genes were studied.
The researchers analysed 23 brains from recently deceased patients, 15 affected by Parkinson’s and 8 control brains. The majority of brains were provided by the UK Parkinson’s Disease Society Tissue Bank at Imperial College London.
Tony Stephenson | alfa
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02.10.2017 | International Institute for Applied Systems Analysis (IIASA)
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Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
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