Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study shows radiation therapy for pelvic cancers increases risk for fractures in older women

23.11.2005


Women urged to talk with their physicians about risks and preventive measures



A University of Minnesota Cancer Center study indicates that older women who receive radiation therapy for treatment of pelvic cancers have an increased risk of hip and other pelvic fractures later in life. Researchers encourage such women to talk with their physicians about their risks and preventive measures, including having their bone density levels checked.

Nancy Baxter, M.D., Ph.D., associate professor and researcher at the University of Minnesota Medical School and Cancer Center, led the research team that conducted this study. Their findings along with an editorial about the study will be published in the Nov. 23, 2005 issue of the Journal of the American Medical Association (JAMA).


Baxter and her colleagues used Surveillance, Epidemiology and End Results (SEER) registry data, which is kept by the National Cancer Institute (NCI) and linked to Medicare, to review the records of 6,428 women. These women were age 65 and older when diagnosed with pelvic malignancies between 1986 through 1999. The researchers’ purpose was to determine whether women who undergo pelvic radiation therapy for pelvic malignancies including cervical, anal, and rectal cancers have a higher rate of pelvic fracture than women with pelvic malignancies who do not receive radiation therapy.

"We found that women who underwent radiation therapy for anal cancer had a three times greater rate of fractures," Baxter says. "Women who had radiation therapy for rectal and cervical cancer had nearly double the rate of fractures.

"We further found that of the 554 women who developed pelvic fractures, 499, or slightly more than 90 percent, were hip fractures," she adds.

The researchers found no significant difference in the rate of arm and spine fractures between women who received pelvic radiation therapy and those who did not.

"Admittedly, the technology used today and the way radiation therapy is given has improved and is better controlled than in the 1980s and 90s," Baxter says. "Nonetheless, our findings point out a concern that women who undergo radiation therapy for pelvic malignancies and their physicians need to be aware of and take precautions to prevent fractures."

She notes that women over age 50 already have about a 17 percent chance of hip fracture in their lifetime because of osteoporosis, or thinning of the bones, that accelerates after menopause. This fact coupled with radiation therapy for pelvic malignancies could put a woman at significant risk for fractures.

Radiation therapy is a common treatment for cervical, anal, and rectal cancer. While it is a proven, effective treatment, Baxter suggests women who have had or are having radiation therapy for pelvic malignancies talk with their physicians about the procedure and follow-up care aimed at preventing factures, including regular checks of the density levels of their bones.

Sara E. Buss | EurekAlert!
Further information:
http://www.umn.edu

More articles from Studies and Analyses:

nachricht WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf

nachricht First form of therapy for childhood dementia CLN2 developed
25.04.2018 | Universitätsklinikum Hamburg-Eppendorf

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>