Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Chemotherapy errors rare, but have potential for serious consequences

25.10.2005


About one out of 30 chemotherapy orders at three ambulatory infusion clinics had errors, and one in 50 orders had a serious error, according to a study appearing in the December 1, 2005 issue of CANCER, a peer-reviewed journal of the American Cancer Society. The study, performed at the Dana-Farber Cancer Institute, found most but not all errors were detected before they reached the patient. None was life-threatening or caused patient harm. Still, an accompanying editorial says the study underscores the need to implement safer controls of drug ordering and dispensing at chemotherapy infusion clinics.

Medication errors in hospitals are a stark reminder of the potential harm that can occur when patients are admitted to the hospital. While most medications are well tolerated, a few classes are toxic and require complex dosing regimens, such as those used in chemotherapy. Even a low error rate from these medications could potentially lead to significant harm, including death.

Aside from a few case reports in journals and popular media, little research has investigated the error rate of chemotherapy orders at outpatient clinics or hospitals. Some individual institutions that have been affected by these reported errors, such as the Dana-Farber Cancer Institute (a member of the Dana-Farber/Harvard Cancer Center, a National Cancer Institute-designated comprehensive cancer center), have made extensive changes to prevent such errors, such as computerization of the medication ordering system.



Led by Tejal K. Gandhi, M.D., M.P.H. and Sylvia B. Bartel, R.Ph., M.H.P., researchers from the Brigham and Women’s Hospital, the Dana-Farber Cancer Institute, and the Harvard School of Public Health reviewed over 10,100 medication orders from one pediatric and two adult ambulatory clinics, which used either a paper or computerized medication ordering system.

The researchers used a strict definition of error and counted any mistake in the medication process, including ordering, dispensing, transcribing, administering, and monitoring.

The review of orders demonstrated an overall medication error rate of three percent and a serious error rate of two percent, less than the five percent rate on all orders identified in previous studies. Categorized according to the severity of the error, 82 percent of the errors in adults and 60 percent in children had the potential to cause an adverse drug event (ADE) had they reached a patient. Of these, approximately 33 percent could have caused serious harm. Nearly half were intercepted by existing systemic checks before they reached the patient and none actually caused an ADE.

In the adult clinics, which used a computerized ordering system, the most frequent errors were due to omission of dosages and orders not being discontinued. In the pediatric clinic, which used a paper-based ordering system, the most frequent errors were due to orders not being discontinued and incorrect dosages.

David Greenberg | EurekAlert!
Further information:
http://www.wiley.com
http://www.interscience.wiley.com/cancer-newsroom

More articles from Studies and Analyses:

nachricht Drone vs. truck deliveries: Which create less carbon pollution?
31.05.2017 | University of Washington

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Quantum thermometer or optical refrigerator?

23.06.2017 | Physics and Astronomy

A 100-year-old physics problem has been solved at EPFL

23.06.2017 | Physics and Astronomy

Equipping form with function

23.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>