Researchers at Fox Chase Cancer Center found no effects of type II diabetes on aggressiveness of prostate cancer but found that long-term survival is worse. The findings were presented today at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology in Denver, Colo.
Previous research suggests that insulin may spur the growth of prostate cancer cells. In type II diabetes, the body fails to properly use insulin, which can lead to an excessive amount of insulin in the blood.
"We looked at several key pretreatment factors used to stage the prostate cancer," explained Khanh H. Nguyen, M.D., lead author of the Fox Chase study and a resident in the radiation oncology department at Fox Chase. "These factors include the initial PSA, Gleason score and T-stage. The men with type II diabetes didnt have a significantly different initial profile for their prostate cancer than the men without diabetes. Additionally, type II diabetes did not appear to influence the rates of PSA failures or distant metastases. However, men with type II diabetes had significantly worse long-term overall survival."
Karen C. Mallet | EurekAlert!
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