A team of researchers led by the University of Toronto has charted how and where a painful event becomes permanently etched in the brain – a discovery that has implications for pain-related emotional disorders such as anxiety and post-traumatic stress.
U of T physiology professor Min Zhuo and his colleagues Professor Bong-Kiun Kaang of Seoul National University in South Korea, and Professor Bao-Ming Li of Fudan University in China have identified where emotional fear memory and pain begin by studying the biochemical processes in a different part of the brain. In a paper published in the Sept.15 issue of Neuron the researchers use mice to show how receptors activated in the pre-frontal cortex, the portion of the brain believed to be involved with higher intellectual functions, play a critical role in the development of fear. Previous research had pointed to activation in the hippocampus, an area buried in the forebrain that regulates emotion and memory, as the origin of fear memory.
"This is critical as it changes how and where scientists thought fear was developed," says Zhuo, the EJLB-CIHR Michael Smith Chair in Neurosciences and Mental Health. "By understanding the biomolecular mechanisms behind fear, we could potentially create therapeutic ways to ease emotional pain in people. Imagine reducing the ability of distressing events, such as amputations, to be permanently imprinted in the brain."
Karen Kelly | EurekAlert!
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
28.04.2017 | Event News
20.04.2017 | Event News
18.04.2017 | Event News
28.04.2017 | Medical Engineering
28.04.2017 | Earth Sciences
28.04.2017 | Life Sciences