Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Aortic aneurysm associated with decreased incidence of atherosclerosis

14.09.2005


Oddly enough, having an aneurysm in the ascending aorta is significantly associated with decreased incidence of atherosclerosis, according to a study by Yale School of Medicine researchers published this month in Chest.



An aortic aneurysm is a widening of the major artery leading from the heart that may rupture, causing hemorrhage, or may split into layers, jeopardizing blood flow to internal organs. When split into layers it is called "aortic dissection."

"This is a silver lining in the cloud of aneurysm disease," said John Elefteriades, M.D., section chief of cardiothoracic surgery in the Department of Surgery and senior author of the study.


He said the study was prompted by clinical observations that patients with aortic aneurysm and dissection-men and women, young and elderly-had a noteworthy absence of atherosclerosis. Most patients, Elefteriades said, begin showing the earliest signs of atherosclerosis in their 20s. "Surprisingly, the arteries of the patients with ascending aortic aneurysm looked like a baby’s or a young child’s," he said.

This study included 64 patients between 36 and 82 years of age with aortic aneurysm or dissection. The control group consisted of 86 trauma patients who had undergone computerized tomography of the chest. The lower prevalence of calcification in patients with ascending aortic aneurysm and dissection was independent of the major risk factors for heart disease-age, gender, high cholesterol, hypertension, diabetes and smoking history. In fact, the aneurysm patients appeared to be significantly protected despite a higher cholesterol level.

In earlier studies Elefteriades and his colleagues demonstrated the heritable nature of ascending aortic aneurysm and dissection. He said it is conceivable that the mutations inherent in aortic aneurysm also play a role in the atherosclerotic process.

"If patients with certain heritable aortic pathologies exhibit decreased systemic atherosclerosis, this finding would be important by virtue of providing new insights into the pathophysiology of the most common cause of death in the western world, heart and blood vessel disease due to atherosclerosis," he said.

Jacqueline Weaver | EurekAlert!
Further information:
http://www.yale.edu

More articles from Studies and Analyses:

nachricht Physics of bubbles could explain language patterns
25.07.2017 | University of Portsmouth

nachricht Obstructing the ‘inner eye’
07.07.2017 | Friedrich-Schiller-Universität Jena

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Carbon Nanotubes Turn Electrical Current into Light-emitting Quasi-particles

Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers

Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...

Im Focus: Flexible proximity sensor creates smart surfaces

Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.

At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

 
Latest News

CCNY physicists master unexplored electron property

26.07.2017 | Physics and Astronomy

Molecular microscopy illuminates molecular motor motion

26.07.2017 | Life Sciences

Large-Mouthed Fish Was Top Predator After Mass Extinction

26.07.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>