Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

UCI neurobiologists uncover evidence of a ’memory code’

12.09.2005


Finding may significantly broaden understanding of how the brain selects and retains information



By examining how sounds are registered during the process of learning, UC Irvine neurobiologists have discovered a neural coding mechanism that the brain relies upon to register the intensity of memories based on the importance of the experience.

While neurobiologists have long hypothesized this type of neural coding, the study presents the first evidence that a "memory code" of any kind may exist. The UCI researchers believe that this code, as well as similar codes that may be discovered, will not only broaden our understanding of normal learning and memory but also may shed light on learning disorders. It may also one day be possible to manipulate these codes to control what and how we remember – not only basic sounds, but complicated information and events.


"This memory code may help explain both good and poor memory," said Norman Weinberger, a professor of neurobiology and behavior in UCI’s Center for the Neurobiology of Learning and Memory. "People tend to remember important experiences better than routine ones."

Weinberger and his colleagues found that when the brain uses this coding method, information is stored in a greater number of brain cells, which should result in a stronger memory. However, the researchers believe that if the brain fails to use the code, the resulting memory – even if it is an important one – would be weaker because fewer neurons would be involved.

Weinberger and postdoctoral researcher Richard Rutkowski discovered this coding system through studying how the primary auditory cortex responds to various sounds.

In the study, the researchers trained rats to press a bar to receive water when they heard a certain tone. The tone was varied in its importance to different rats as shown by their different levels of correct performance.

After brain mapping these test rats, the researchers found that the greater the importance of the tone, the greater the area of the auditory cortex that became tuned to it. The results in rats that received the same tones but were trained to a visual stimulus did not differ from those in untrained rats, showing that the behavioral importance of the tone, not its mere presence, was the critical factor.

Study results appear on the Online Early Edition of the Proceedings of the National Academy of Sciences. The National Institute on Deafness and Other Communication Disorders supported the effort.

About the University of California, Irvine: Celebrating 40 years of innovation, the University of California, Irvine is a top-ranked university dedicated to research, scholarship and community service. Founded in 1965, UCI is among the fastest-growing University of California campuses, with more than 24,000 undergraduate and graduate students and about 1,400 faculty members. The second-largest employer in dynamic Orange County, UCI contributes an annual economic impact of $3 billion.

Tom Vasich | EurekAlert!
Further information:
http://www.today.uci.edu
http://www.uci.edu

More articles from Studies and Analyses:

nachricht The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung

nachricht A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>